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PDBe
RCSB
PDBj
7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt▲ | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3MZG_A_B | HA180A | HA167A | COR | 3MZG_A_B,3N06_A_B... | 1.28E-06 | 1.05E-07 | Prolactin | Prolactin receptor | 298 | 5.15E+04 | 4.72E+04 | 6.58E-02 | 4.97E-03 | None | None | None | None | SPR | |||
3MZG_A_B | HB188A | HB188A | COR | 3MZG_A_B,3N06_A_B... | 3.6E-06 | 1.05E-07 | Prolactin | Prolactin receptor | 298 | 5.9E+04 | 4.72E+04 | 2.12E-01 | 4.97E-03 | None | None | None | None | SPR | |||
3MZG_A_B | HA180A,HB188A | HA167A,HB188A | COR,COR | 3MZG_A_B,3N06_A_B... | 2.9E-05 | 1.05E-07 | Prolactin | Prolactin receptor | 298 | 2.8E+04 | 4.72E+04 | 8E-01 | 4.97E-03 | None | None | None | None | SPR | |||
1MHP_HL_A | SL28Q | SL27Q | RIM | AB/AG | AB/AG | 4.3E-09 | 1.07E-08 | AQC2 fab | Integrin alpha-1 | 298(assumed) | 2.5E+05 | 2.5E+05 | 1.1E-03 | 2.6E-03 | None | None | None | None | SPR | ||
1MHP_HL_A | TH50V,SL28Q,NL52Y | TH50V,SL27Q,NL51Y | SUP,RIM,SUR | AB/AG | AB/AG | 1.9E-09 | 1.07E-08 | AQC2 fab | Integrin alpha-1 | 298(assumed) | 3.7E+05 | 2.5E+05 | 7E-04 | 2.6E-03 | None | None | None | None | SPR | ||
2B42_A_B | HA374A | HA357A | COR | 2B42_A_B | 1.7E-08 | 1.07E-09 | TAXI-I | B. subtilis endoxylanase | 295 | 1.17E+05 | 3.61E+05 | 1.59E-03 | 3.6E-04 | None | None | None | None | SPR | |||
2B42_A_B | HA374Q | HA357Q | COR | 2B42_A_B | 6.58E-09 | 1.07E-09 | TAXI-I | B. subtilis endoxylanase | 295 | 2.56E+05 | 3.61E+05 | 1.18E-03 | 3.6E-04 | None | None | None | None | SPR | |||
2B42_A_B | HA374K | HA357K | COR | 2B42_A_B | 8.16E-08 | 1.07E-09 | TAXI-I | B. subtilis endoxylanase | 295 | 4.57E+04 | 3.61E+05 | 3.44E-03 | 3.6E-04 | None | None | None | None | SPR | |||
1DVF_AB_CD | HA30A | HA30A | RIM | AB/AG | AB/AG | 1.75E-07 | 1.08E-08 | IgG1-kappa D1.3 Fv | E5.2 Fv | 298 | None | None | None | None | SPR | ||||||
1DVF_AB_CD | YA32A | YA32A | COR | AB/AG | AB/AG | 3.33E-07 | 1.08E-08 | IgG1-kappa D1.3 Fv | E5.2 Fv | 298 | None | None | None | None | SPR |