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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt▲ | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2I26_N_L | SN61R | SN60R | SUR | 2I26_N_L | 3.3E-09 | 9.5E-09 | Type II IgNAR | HEW Lysozyme | 298 | 3.5E+05 | 2.1E+05 | 1.2E-03 | 2E-03 | None | None | None | None | SPR | |||
3BIW_A_E | LA399A,NA400A,DA402N | LA317A,NA318A,DA320N | COR,COR,SUP | 3BIW_A_E | n.b | 9.7E-08 | Neuroligin-1 | Neurexin-1-beta | 293 | None | None | None | None | ITC | |||||||
1FY8_E_I | DE194N | DE168N | INT | Pr/PI | Pr/PI | 1.2E-05 | 9E-06 | Mutant trypsinogen | BPTI | 298 | None | None | None | None | ITC | ||||||
1FY8_E_I | QE156K | QE128K | INT | Pr/PI | Pr/PI | 6.5E-05 | 9E-06 | Mutant trypsinogen | BPTI | 298 | None | None | None | None | ITC | ||||||
1AO7_ABC_DE | YC5F | YC5F | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.2E-06 | 9E-07 | HLA-A2 plus tax peptide | A6 TCR | 277 | 5.90 | 4.40 | 48.00 | 44.00 | ITC | ||||||
4L0P_A_B | TA37K | TA11K | SUR | 4L0P_A_B,2HLE_A_B | 9E-09 | 9E-09 | Ephrin type-A receptor 3 | Ephrin-A5 | 298(assumed) | None | None | None | None | ELISA | |||||||
4L0P_A_B | SA46F | SA20F | SUR | 4L0P_A_B,2HLE_A_B | 9.9E-09 | 9E-09 | Ephrin type-A receptor 3 | Ephrin-A5 | 298(assumed) | None | None | None | None | ELISA | |||||||
4L0P_A_B | EA53K | EA27K | COR | 4L0P_A_B,2HLE_A_B | 8.1E-07 | 9E-09 | Ephrin type-A receptor 3 | Ephrin-A5 | 298(assumed) | None | None | None | None | ELISA | |||||||
4L0P_A_B | NA85S | NA59S | INT | 4L0P_A_B,2HLE_A_B | 1.53E-08 | 9E-09 | Ephrin type-A receptor 3 | Ephrin-A5 | 298(assumed) | None | None | None | None | ELISA | |||||||
4L0P_A_B | TA102Q | TA76Q | SUP | 4L0P_A_B,2HLE_A_B | 1.08E-07 | 9E-09 | Ephrin type-A receptor 3 | Ephrin-A5 | 298(assumed) | None | None | None | None | ELISA |