SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Dh Mut▲	Dh Wt	Ds Mut	Ds Wt	Method
3M62_A_B	QB52A	QB50A	RIM	3M62_A_B,3M63_A_B	4.15E-07	7E-08	Ubiquitin conjugation factor E4	Rad23	298	-6.20	-17.30	8.39	-24.80	ITC
2DVW_A_B	RB338A,RB342A	RB3A,RB7A	COR,COR	2DVW_A_B,4HRN_A_D...	2.55E-06	6.73E-08	Gankyrin	S6 ATPase	298	-6.10	-28.70	5.033557047	-63.76	ITC
4G0N_A_B	QB66A,RA41A	QB13A,RA41A	COR,COR	4G0N_A_B,3KUD_A_B...	6.71E-07	8.02E-08	H-Ras1	Raf-RBD	308	-6.10	-8.60	8.4415584416	4.55	ITC
3WWN_A_B	RA227E	RA221E	RIM	3WWN_A_B	3.75E-06	6.62E-06	LysZ	LysW	333	-6.03	-6.36	6.1561561562	4.02	ITC
1LFD_A_B	KA52A	KA39A	COR	1LFD_A_B,4G0N_A_B...	3.98E-05	6.91E-07	RalGDS-RBD	H-Ras1	298	-6.00	-11.20	-0.3355704698	-9.3959731544	ITC
4G0N_A_B	DA38A	DA38A	COR	4G0N_A_B,3KUD_A_B...	1.76E-05	8.02E-08	H-Ras1	Raf-RBD	308	-6.00	-8.60	2.2727272727	4.55	ITC
4G0N_A_B	RB59A,DA33A	RB6A,DA33A	RIM,RIM	4G0N_A_B,3KUD_A_B...	5.61E-06	8.02E-08	H-Ras1	Raf-RBD	308	-6.00	-8.60	4.5454545455	4.55	ITC
2PCC_A_B	EA290A	EA290A	RIM	2B0Z_A_B,2B10_A_B...	4.05E-02	1.15E-06	Cytochrome C peroxidase	Cytochrome C	298	-5.80	-2.60	-13.10	18.40	ITC
4G0N_A_B	TB68A,EA31A	TB15A,EA31A	SUP,RIM	4G0N_A_B,3KUD_A_B...	1.1E-06	8.02E-08	H-Ras1	Raf-RBD	308	-5.80	-8.60	8.4415584416	4.55	ITC
1LFD_A_B	KA32A	KA19A	COR	1LFD_A_B,4G0N_A_B...	1.44E-05	6.91E-07	RalGDS-RBD	H-Ras1	298	-5.70	-11.20	3.0201342282	-9.3959731544	ITC