SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut	Koff Wt	Dh Mut	Dh Wt	Ds Mut▲	Ds Wt	Method
2PCC_A_B	AB81G,VA197A	AB86G,VA197A	RIM,COR	2B0Z_A_B,2B10_A_B...	4E-05	1.15E-06	Cytochrome C peroxidase	Cytochrome C	298					-2.20	-2.60	12.70	18.40	ITC
1GUA_A_B	TB68A	TB13A	SUP	1GUA_A_B,1C1Y_A_B...	1.61E-06	4.93E-07	Rap1a	Raf-RBD	298					-4.20	-5.60	12.7516778523	10.067114094	ITC
1GUA_A_B	VB69A,EA37A	VB14A,EA37A	COR,COR	1GUA_A_B,1C1Y_A_B...	8.7E-06	4.93E-07	Rap1a	Raf-RBD	298					-3.30	-5.60	12.7516778523	10.067114094	ITC
1BRS_A_D	DD39A	DD39A	COR	1BRS_A_D,1B2U_A_D...	4.06E-09	1E-14	Barnase	Barstar	298	1.9E+08	3.7E+08	9E-01	3.73E-06	-7.40	-19.30	13.10	-1.01	ITC
1JTG_A_B	FB142A	FB142A	COR	1XXM_A_C,1S0W_A_C...	2.63E-08	1.11E-10	TEM-1 beta-lactamase	BLIP	303					-6.50	-7.40	13.30	21.10	ITC
2C0L_A_B	QA586R	QA239R	INT	2C0L_A_B,3R9A_AC_B	1.34E-06	1.09E-07	TRP region of PEX5	Sterol carrier protein 2	305					-4.16	-10.10	13.40	-0.962	ITC
1GUA_A_B	VB69A	VB14A	COR	1GUA_A_B,1C1Y_A_B...	5.84E-07	4.93E-07	Rap1a	Raf-RBD	298					-4.50	-5.60	13.4228187919	10.067114094	ITC
2REX_A_B	YB114F	YB97F	RIM	2REX_A_B,3Q3J_A_B...	5.5E-06	5.5E-06	Plexin-B1	Rnd-1	298					-2.50	-6.70	14.00	1.68	ITC
1GUA_A_B	QB66A	QB11A	COR	1GUA_A_B,1C1Y_A_B...	5.84E-07	4.93E-07	Rap1a	Raf-RBD	298					-4.30	-5.60	14.0939597315	10.067114094	ITC
4G0N_A_B	NB64A	NB11A	RIM	4G0N_A_B,3KUD_A_B...	1.67E-07	8E-08	H-Ras1	Raf-RBD	298					-5.00	-5.20	14.4295302013	15.100671141	ITC