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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut▲ | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3M62_A_B | RA92A | RA98A | RIM | 3M62_A_B,3M63_A_B | 2.65E-07 | 7E-08 | Ubiquitin conjugation factor E4 | Rad23 | 298 | -3.40 | -17.30 | 18.80 | -24.80 | ITC | |||||||
1JTG_A_B | YB50A | YB50A | COR | 1XXM_A_C,1S0W_A_C... | 3.33E-12 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 303 | -10.20 | -7.40 | 18.852616789 | 21.10 | ITC | |||||||
2PCC_A_B | KB87A,VA197A | KB92A,VA197A | RIM,COR | 2B0Z_A_B,2B10_A_B... | 1.45E-05 | 1.15E-06 | Cytochrome C peroxidase | Cytochrome C | 298 | -0.90 | -2.60 | 19.10 | 18.40 | ITC | |||||||
1GUA_A_B | RB59A,EA37A | RB4A,EA37A | RIM,COR | 1GUA_A_B,1C1Y_A_B... | 4.43E-06 | 4.93E-07 | Rap1a | Raf-RBD | 298 | -1.50 | -5.60 | 19.4630872483 | 10.067114094 | ITC | |||||||
4G0N_A_B | RA41A | RA41A | COR | 4G0N_A_B,3KUD_A_B... | 6.67E-08 | 8E-08 | H-Ras1 | Raf-RBD | 298 | -4.00 | -5.20 | 19.4630872483 | 15.100671141 | ITC | |||||||
2PCC_A_B | KB72A,EA290A | KB77A,EA290A | RIM,RIM | 2B0Z_A_B,2B10_A_B... | 7.39E-06 | 1.15E-06 | Cytochrome C peroxidase | Cytochrome C | 298 | -1.20 | -2.60 | 19.50 | 18.40 | ITC | |||||||
2KSO_A_B | KA23D | KA10D | COR | 2KSO_A_B | 9.1E-06 | 5.2E-06 | Ephrin type-A receptor 2 SAM | SHIP2 SAM | 298(assumed) | -0.85 | -2.50 | 19.7986577181 | 15.7718120805 | ITC | |||||||
1BRS_A_D | EA73Y | EA71Y | SUP | 1BRS_A_D,1B2U_A_D... | 5.88E-13 | 1E-14 | Barnase | Barstar | 298 | -10.70 | -19.30 | 19.80 | -1.01 | ITC | |||||||
1JTG_A_B | RB144A | RB144A | RIM | 1XXM_A_C,1S0W_A_C... | 8.17E-10 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 303 | -6.60 | -7.40 | 19.801980198 | 21.10 | ITC | |||||||
1JTG_A_B | FB36A | FB36A | COR | 1XXM_A_C,1S0W_A_C... | 4.76E-08 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 298 | -4.10 | -7.40 | 19.90 | 21.10 | ITC |