SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Dh Mut	Dh Wt	Ds Mut	Ds Wt▲	Method
1GUA_A_B	KB84A	KB29A	RIM		1GUA_A_B,1C1Y_A_B...	1.44E-05	4.93E-07	Rap1a	Raf-RBD	298	-4.30	-5.60	7.7181208054	10.067114094	ITC
1GUA_A_B	KB87A	KB32A	RIM		1GUA_A_B,1C1Y_A_B...	1.9E-06	4.93E-07	Rap1a	Raf-RBD	298	-4.20	-5.60	12.0805369128	10.067114094	ITC
1GUA_A_B	VB88A	VB33A	COR		1GUA_A_B,1C1Y_A_B...	6.91E-07	4.93E-07	Rap1a	Raf-RBD	298	-6.80	-5.60	5.3691275168	10.067114094	ITC
1GUA_A_B	EA37A	EA37A	COR		1GUA_A_B,1C1Y_A_B...	4.43E-06	4.93E-07	Rap1a	Raf-RBD	298	-2.70	-5.60	15.4362416107	10.067114094	ITC
1GUA_A_B	SA39A	SA39A	COR		1GUA_A_B,1C1Y_A_B...	5.24E-06	4.93E-07	Rap1a	Raf-RBD	298	-8.00	-5.60	-2.3489932886	10.067114094	ITC
1GUA_A_B	RB59A,EA37A	RB4A,EA37A	RIM,COR		1GUA_A_B,1C1Y_A_B...	4.43E-06	4.93E-07	Rap1a	Raf-RBD	298	-1.50	-5.60	19.4630872483	10.067114094	ITC
1GUA_A_B	VB69A,EA37A	VB14A,EA37A	COR,COR		1GUA_A_B,1C1Y_A_B...	8.7E-06	4.93E-07	Rap1a	Raf-RBD	298	-3.30	-5.60	12.7516778523	10.067114094	ITC
2GOX_A_B	RB131A	RB31A	COR		2GOX_A_B,3D5S_A_C...	2.6E-08	2E-09	Complement C3d	Fibrinogen-binding protein Efb-C	298	-3.90	-8.50	21.50	11.40	ITC
2GOX_A_B	NB138A	NB38A	COR		2GOX_A_B,3D5S_A_C...	1.9E-08	2E-09	Complement C3d	Fibrinogen-binding protein Efb-C	298	-5.50	-8.50	16.80	11.40	ITC
1LP9_ABC_EF	KA66A	KA66A	SUP	TCR/pMHC	TCR/pMHC,1JCK_A_B	7E-06	1E-06	HLA-A2 plus P1049 peptide	AHIII TCR	298	-0.60	-3.90	21.10	14.80	ITC