SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
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7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut▲
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1AK4_A_D
AD492V
AD92V
RIM
1AK4_A_D,1M9E_A_D
2.2E-05
1.2E-05
Cyclophilin A
HIV-1 capsid protein
298(assumed)
None
None
None
None
SPR
1AK4_A_D
PD493A
PD93A
RIM
1AK4_A_D,1M9E_A_D
3.8E-05
1.2E-05
Cyclophilin A
HIV-1 capsid protein
298(assumed)
None
None
None
None
SPR
1AK4_A_D
LD483T,VD486P,HD4...
LD83T,VD86P,HD87A...
SUR,COR,RIM,COR,R...
1AK4_A_D,1M9E_A_D
4.2E-05
1.2E-05
Cyclophilin A
HIV-1 capsid protein
298(assumed)
None
None
None
None
SPR
1M9E_A_D
AD87H
AD76H
RIM
1AK4_A_D,1M9E_A_D
1.2E-05
6.6E-05
Cyclophilin A
HIV-1 capsid protein
298(assumed)
None
None
None
None
SPR
2HLE_A_B
KA149Q
KA141Q
COR
2HLE_A_B,4L0P_A_B
2E-08
4E-08
Ephrin type-B receptor 4
Ephrin-B2
298
3.70
3.30
48.30
44.90
ITC
2HLE_A_B
LA95R
LA87R
SUP
2HLE_A_B,4L0P_A_B
1.9E-06
4E-08
Ephrin type-B receptor 4
Ephrin-B2
298
5.20
3.30
43.60
44.90
ITC
3BT1_A_U
RU137A
RU135A
INT
3BT1_A_U
5.6E-10
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
KU139A
KU137A
RIM
3BT1_A_U
2.84E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
RU142A
RU140A
SUR
3BT1_A_U
1.68E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
HU143A
HU141A
INT
3BT1_A_U
2.78E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
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