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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut▲ | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3LB6_A_C | FA107A | FA103A | COR | 3LB6_A_C,3G6D_LH_... | 8.91E-11 | 1.58E-14 | Interleukin-13 | Interleukin-13 receptor subunit alpha-2 | 298(assumed) | 1.15E+07 | 1.22E+08 | 9.45E-04 | 1.93E-06 | None | None | None | None | SPR | |||
2AK4_ABC_DE | TA69A | TA69A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.05E-05 | 1.87E-05 | HLA-B35 plus LPEP viral peptide | SB27 TCR | 298 | 9.79E+04 | 6.56E+04 | 9.4E-02 | 1.2E-01 | None | None | None | None | SPR | ||
1JTG_A_B | WB162A | WB162A | COR | 1XXM_A_C,1S0W_A_C... | 2.48E-07 | 4.77E-09 | TEM-1 beta-lactamase | BLIP | 298 | 6.43E+04 | 6.7E+04 | 9.4E-03 | 1.5E-04 | None | None | None | None | SPR | |||
1A4Y_A_B | KA320A | KA320A | COR | 1A4Y_A_B,1Z7X_W_X | 3.2E-16 | 5.4E-16 | Ribonuclease inhibitor | Angiogenin | 298 | 2.9E+08 | 2E+08 | 9.4E-08 | 1.1E-07 | None | None | None | None | SFFL | |||
1EMV_A_B | VA34A | VA32A | COR | 2VLP_A_B,2VLN_A_B... | 1.26E-12 | 1.62E-14 | Colicin E9 immunity protein | Colicin E9 DNase | 298 | 7.57E+07 | 1.13E+08 | 9.54E-05 | 1.83E-06 | None | None | None | None | SFFL | |||
3BT1_A_U | NU190A | NU188A | SUR | 3BT1_A_U | 3.1E-10 | 4.6E-10 | Urokinase-type plasminogen activator | Urokinase plasminogen activator surface receptor | 293 | 3.07E+05 | 3.98E+05 | 9.5E-05 | 1.77E-04 | None | None | None | None | SPR | |||
3MZW_A_B | NB6E,NB23T,AB42S,... | NB1E,NB18T,AB37S,... | RIM,SUR,SUR,SUR,SUR | 3MZW_A_B,1FC2_C_D... | 3.7E-11 | 2.3E-11 | Affibody ZHER2:342 | erbB-2 | 298(assumed) | 2.6E+06 | 4E+06 | 9.5E-05 | 8.8E-05 | None | None | None | None | SPR | |||
1JTD_A_B | YB113A | YB75A | COR | 1JTD_A_B,1XXM_A_C... | 1.08E-12 | 4.8E-13 | TEM-1 beta-lactamase | BLIP-II | 298(assumed) | 8.8E+06 | 7.7E+06 | 9.5E-06 | 3.7E-06 | None | None | None | None | IASP | |||
1JRH_LH_I | NI48Q | NI38Q | SUP | AB/AG | AB/AG | 2.66E-08 | 1.44E-08 | mAbs A6 | Interferon gamma receptor | 298 | 3.53E+05 | 6.09E+05 | 9.62E-03 | 8.75E-03 | None | None | None | None | SPR | ||
3QHY_A_B | IB229A | IB189A | SUP | 3QHY_A_B,1JTD_A_B... | 5.32E-11 | 3E-13 | B. anthracis beta-lactamase | BLIP-II | 298(assumed) | 1.8E+06 | 1.9E+06 | 9.67E-05 | 6E-07 | None | None | None | None | IASP |