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PDBe
RCSB
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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut▲ | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2QJB_AB_C | TC74A,LC78M,GC79K... | TC43A,LC47M,GC48K... | INT,SUP,COR,SUR,S... | 1REW_AB_C,2QJ9_AB... | 2.4E-09 | 4.9E-09 | Bone morphogenetic protein-2 | BMPR-IA receptor | 298(assumed) | 4E+05 | 2.8E+05 | 9.7E-04 | 1.11E-03 | None | None | None | None | SPR | |||
1JTD_A_B | NA100A | NA74A | RIM | 1JTD_A_B,1XXM_A_C... | 5.8E-12 | 1.5E-12 | TEM-1 beta-lactamase | BLIP-II | 296 | 1.7E+06 | 1.9E+06 | 9.7E-06 | 2.9E-06 | None | None | None | None | SFFL | |||
1JTG_A_B | FB142A | FB142A | COR | 1XXM_A_C,1S0W_A_C... | 3.29E-07 | 4.77E-09 | TEM-1 beta-lactamase | BLIP | 298 | 6.5E+04 | 6.7E+04 | 9.8E-03 | 1.5E-04 | None | None | None | None | SPR | |||
3MZW_A_B | NB23T,AB54S | NB18T,AB49S | SUR,SUR | 3MZW_A_B,1FC2_C_D... | 2.7E-11 | 2.3E-11 | Affibody ZHER2:342 | erbB-2 | 298(assumed) | 3.7E+06 | 4E+06 | 9.8E-05 | 8.8E-05 | None | None | None | None | SPR | |||
1A4Y_A_B | EA344A | EA344A | COR | 1A4Y_A_B,1Z7X_W_X | 7.3E-16 | 5.4E-16 | Ribonuclease inhibitor | Angiogenin | 298 | 1.4E+08 | 2E+08 | 9.8E-08 | 1.1E-07 | None | None | None | None | SFFL | |||
3BT1_A_U | LU168A | LU166A | SUP | 3BT1_A_U | 1.62E-09 | 4.6E-10 | Urokinase-type plasminogen activator | Urokinase plasminogen activator surface receptor | 293 | 6.13E+05 | 3.98E+05 | 9.92E-04 | 1.77E-04 | None | None | None | None | SPR | |||
2BNR_ABC_DE | EA58A | EA58A | RIM | TCR/pMHC | TCR/pMHC,1JCK_A_B... | 3.2E-06 | 3.2E-06 | HLA-A2 plus NY-ESO peptide | 1G4 TCR | 298 | 2.376238E+04 | 2.4E+04 | 9.9E-02 | 1E-01 | None | None | None | None | SPR | ||
1Z7X_W_X | WW375A | WW375A | COR | 1Z7X_W_X,1A4Y_A_B | 7.2E-13 | 4.3E-14 | Ribonuclease inhibitor | RNase A | 298 | 1.4E+08 | 2.8E+08 | 9.9E-05 | 1.2E-05 | None | None | None | None | SFFL | |||
3L5X_A_HL | NL92F,EL93W,YL94G | NL92F,EL93W,YL94G | RIM,SUR,SUR | AB/AG | AB/AG,3LB6_A_C | 9.4E-11 | 7.54E-10 | Interleukin-13 | H2L6 fab | 298 | 1.06E+06 | 1.25E+06 | 9.9E-05 | 9.4E-04 | None | None | None | None | SPR | ||
1BRS_A_D | DD39A | DD39A | COR | 1BRS_A_D,1B2U_A_D... | 4.06E-09 | 1E-14 | Barnase | Barstar | 298 | 1.9E+08 | 3.7E+08 | 9E-01 | 3.73E-06 | -7.40 | -19.30 | 13.10 | -1.01 | ITC |