SKEMPI v2.0

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Mutations

7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Ref.	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut▲	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
3MZW_A_B	NB6A,NB23T,SB33K,...	NB1A,NB18T,SB28K,...	RIM,SUR,SUR,SUR,S...		3MZW_A_B,1FC2_C_D...	1.6E-11	2.3E-11		Affibody ZHER2:342	erbB-2	298(assumed)	5.7E+06	4E+06	9E-05	8.8E-05	None	None	None	None	SPR
5C6T_HL_A	IA299A	IA201A	SUP	AB/AG	AB/AG	5.8E-10	1.3E-10		1G2 fab	HCMV glycoprotein B	298(assumed)	1.55E+05	2.95E+05	9E-05	3.75E-05	None	None	None	None	SPR
1BJ1_HL_VW	HH101Y,YH103R,SH105T	HH101Y,YH103R,SH105T	COR,RIM,RIM	AB/AG	AB/AG	4E-10	2.9E-09		Fab-12	VEGF	298	2.6E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1BJ1_HL_VW	HH101Y,YH103R,GH1...	HH101Y,YH103R,GH1...	COR,RIM,RIM,RIM	AB/AG	AB/AG	8E-10	2.9E-09		Fab-12	VEGF	298	1.2E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,RIM	AB/AG	AB/AG	4E-10	<1.4E-10		Fab-12	VEGF	298	2.6E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,RIM,RIM	AB/AG	AB/AG	8E-10	<1.4E-10		Fab-12	VEGF	298	1.2E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1A4Y_A_B	YA437F	YA437F	COR		1A4Y_A_B,1Z7X_W_X	5.9E-16	3.9E-16		Ribonuclease inhibitor	Angiogenin	298	1.5E+08	2.8E+08	9E-08	1.1E-07	None	None	None	None	SFFL
2FTL_E_I	TI11A	TI11A	RIM	Pr/PI	Pr/PI	<5E-11	5E-14		Bovine trypsin	BPTI	295	3.5E+05	9.9E+05	<1.7E-05	5E-08	None	None	None	None	IASP
2FTL_E_I	KI46A	KI46A	SUR	Pr/PI	Pr/PI	<5E-11	5E-14		Bovine trypsin	BPTI	295	5.5E+05	9.9E+05	<2.3E-05	5E-08	None	None	None	None	IASP
2FTL_E_I	FI33A	FI33A	INT	Pr/PI	Pr/PI	<5E-11	5E-14		Bovine trypsin	BPTI	295	4.7E+05	9.9E+05	<2.4E-05	5E-08	None	None	None	None	IASP