SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
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>
<=
>=
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in
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starts with
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not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt▲
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1TM1_E_I
MI59K
MI40K
COR
Pr/PI
Pr/PI
1.9E-11
3E-12
Subtilisin BPN
Chymotrypsin inhibitor 2
298(assumed)
None
None
None
None
IASP
1TM1_E_I
MI59Y
MI40Y
COR
Pr/PI
Pr/PI
3.3E-12
3E-12
Subtilisin BPN
Chymotrypsin inhibitor 2
298(assumed)
None
None
None
None
IASP
1TM1_E_I
MI59F
MI40F
COR
Pr/PI
Pr/PI
1.7E-11
3E-12
Subtilisin BPN
Chymotrypsin inhibitor 2
298(assumed)
None
None
None
None
IASP
1TM1_E_I
YI61A
YI42A
COR
Pr/PI
Pr/PI
4.6E-10
3E-12
Subtilisin BPN
Chymotrypsin inhibitor 2
298(assumed)
None
None
None
None
IASP
2SIC_E_I
MI73K
MI67K
COR
Pr/PI
Pr/PI
1.8E-11
1.8E-11
Subtilisin BPN
Streptomyces subtilisin inhibitor
298
None
None
None
None
IASP
2SIC_E_I
MI73R
MI67R
COR
Pr/PI
Pr/PI
1.8E-11
1.8E-11
Subtilisin BPN
Streptomyces subtilisin inhibitor
298
None
None
None
None
IASP
1IAR_A_B
EA9K
EA9K
COR
1IAR_A_B
n.b
1.62E-10
Interleukin-4
Interleukin-4 receptor
298
None
None
None
None
SPR
1IAR_A_B
EA9A
EA9A
COR
1IAR_A_B
n.b
1.62E-10
Interleukin-4
Interleukin-4 receptor
298
None
None
None
None
SPR
1IAR_A_B
RA88D
RA88D
COR
1IAR_A_B
n.b
1.62E-10
Interleukin-4
Interleukin-4 receptor
298
None
None
None
None
SPR
1IAR_A_B
NA89R
NA89R
SUP
1IAR_A_B
n.b
1.62E-10
Interleukin-4
Interleukin-4 receptor
298
None
None
None
None
SPR
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