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RCSB
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7085 records found
| PDB Code | Mutation Pdb | Mutation Cleaned▲ | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3HFM_HL_Y | YH33F | YH33F | COR | AB/AG | AB/AG | 1.41E-08 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -17.50 | -21.90 | -21.80 | -32.60 | ITC | ||||||
| 3HFM_HL_Y | YH33L | YH33L | COR | AB/AG | AB/AG | 6.67E-08 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -16.10 | -21.90 | -20.40 | -32.60 | ITC | ||||||
| 3HFM_HL_Y | YH33W | YH33W | COR | AB/AG | AB/AG | 4.35E-08 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -15.70 | -21.90 | -18.10 | -32.60 | ITC | ||||||
| 4OZG_ABJ_GH | YH55F | YH46F | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.3E-06 | 1.58E-05 | HLA-DQ plus gliadin-alpha2 peptide | D2 TCR | 293 | None | None | None | None | SPR | ||||||
| 3HFM_HL_Y | YH50A | YH50A | SUP | AB/AG | AB/AG | 7E-06 | 3E-11 | HyHEL-10 | HEW Lysozyme | 298(assumed) | None | None | None | None | SP | ||||||
| 3HFM_HL_Y | YH50A,RY21A | YH50A,RY21A | SUP,COR | AB/AG | AB/AG | 2E-05 | 3E-11 | HyHEL-10 | HEW Lysozyme | 298(assumed) | None | None | None | None | SP | ||||||
| 3HFM_HL_Y | YH50F | YH50F | SUP | AB/AG | AB/AG | 3.45E-08 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -14.30 | -21.90 | -13.20 | -32.60 | ITC | ||||||
| 3HFM_HL_Y | YH50L | YH50L | SUP | AB/AG | AB/AG | 2.7E-07 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -12.90 | -21.90 | -12.50 | -32.60 | ITC | ||||||
| 3HFM_HL_Y | YH53A | YH53A | COR | AB/AG | AB/AG | 5.26E-07 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -14.40 | -21.90 | -18.80 | -32.60 | ITC | ||||||
| 3HFM_HL_Y | YH53F | YH53F | COR | AB/AG | AB/AG | 6.67E-09 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -20.20 | -21.90 | -29.30 | -32.60 | ITC |