SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
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<=
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starts with
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in
not in
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<
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<=
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starts with
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in
not in
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!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned▲
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1R0R_E_I
YI20R
YI15R
COR
Pr/PI
Pr/PI
5.56E-08
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20S
YI15S
COR
Pr/PI
Pr/PI
1.79E-07
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20T
YI15T
COR
Pr/PI
Pr/PI
3.03E-07
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20V
YI15V
COR
Pr/PI
Pr/PI
1.1E-08
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20W
YI15W
COR
Pr/PI
Pr/PI
1.59E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20A
YI17A
COR
Pr/PI
Pr/PI
3.85E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20C
YI17C
COR
Pr/PI
Pr/PI
3.85E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20D
YI17D
COR
Pr/PI
Pr/PI
2.17E-07
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20D
YI17D
COR
Pr/PI
Pr/PI
1.59E-07
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20E
YI17E
COR
Pr/PI
Pr/PI
2.5E-08
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
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