SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned▲
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1PPF_E_I
YI20F
YI20F
COR
Pr/PI
Pr/PI
3.7E-10
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20G
YI20G
COR
Pr/PI
Pr/PI
1.92E-07
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20H
YI20H
COR
Pr/PI
Pr/PI
9.09E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20H
YI20H
COR
Pr/PI
Pr/PI
1.03E-08
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20I
YI20I
COR
Pr/PI
Pr/PI
1.25E-07
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20K
YI20K
COR
Pr/PI
Pr/PI
3.23E-07
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20L
YI20L
COR
Pr/PI
Pr/PI
1.67E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20M
YI20M
COR
Pr/PI
Pr/PI
1.89E-08
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20N
YI20N
COR
Pr/PI
Pr/PI
7.69E-08
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20P
YI20P
COR
Pr/PI
Pr/PI
1.41E-06
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
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