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RCSB
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7085 records found
| PDB Code | Mutation Pdb | Mutation Cleaned | Location▲ | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1DAN_HL_UT | NU199A,RU200A | NU105A,RU106A | SUR,SUR | 1DAN_HL_UT | 1.21E-08 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 2.34E+05 | 3.4E+05 | 2.86E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | TU197A,VU198A | TU103A,VU104A | SUR,SUR | 1DAN_HL_UT | 4.79E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 4.34E+05 | 3.4E+05 | 2.07E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | EU183A,NU184A | EU89A,NU90A | SUR,SUR | 1DAN_HL_UT | 5.26E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 4.02E+05 | 3.4E+05 | 2.14E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | KU165A,KU166A | KU71A,KU72A | SUR,SUR | 1DAN_HL_UT | 4.11E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 3.52E+05 | 3.4E+05 | 1.69E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | KU149A,DU150A | KU59A,DU60A | SUR,SUR | 1DAN_HL_UT | 5.19E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 3.09E+05 | 3.4E+05 | 1.63E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | QU114A,EU117A | QU24A,EU27A | SUR,SUR | 1DAN_HL_UT | 6.52E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 2.6E+05 | 3.4E+05 | 1.74E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | LU104A,EU105A | LU14A,EU15A | SUR,SUR | 1DAN_HL_UT | 2.82E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 6.66E+05 | 3.4E+05 | 1.88E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | KT68A,QT69A | KT63A,QT64A | SUR,SUR | 1DAN_HL_UT | 4.35E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 4.3E+05 | 3.4E+05 | 1.88E-03 | 2.1E-03 | None | None | None | None | SPR | |||
| 1DAN_HL_UT | KT65A,DT66A | KT60A,DT61A | SUR,SUR | 1DAN_HL_UT | 2.63E-09 | 6.16E-09 | Factor VIIa | Tissue factor | 298 | 2.56E+05 | 3.4E+05 | 6.85E-04 | 2.1E-03 | None | None | None | None | SPR | |||
| 5E9D_AB_CDE | GD28E,VE50D | GD27E,VE49D | SUR,SUR | TCR/pMHC | TCR/pMHC,4N8V_G_ABC | 1.8E-08 | 1.37E-07 | HLA-A2 plus MART-1 peptide | RD1-MART1 TCR | 298(assumed) | None | None | None | None | FL |