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PDBe
RCSB
PDBj
7085 records found
| PDB Code | Mutation Pdb▲ | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3S9D_A_B | AA57H,AA58E,AA61Q | AA43H,AA44E,AA47Q | INT,INT,SUR | 3S9D_A_B,3SE3_B_C... | 6.7E-10 | 6.9E-10 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 1E+07 | 1E+07 | 6.7E-03 | 6.9E-03 | None | None | None | None | SP | |||
| 3S9D_A_B | AA57H,AA58E,AA61Q | AA43H,AA44E,AA47Q | INT,INT,SUR | 3S9D_A_B,3SE3_B_C... | 5E-09 | 5E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 3E+06 | 3E+06 | 1.5E-02 | 1.5E-02 | None | None | None | None | SP | |||
| 3S9D_A_B | AA57Y,AA58N,AA61S | AA43Y,AA44N,AA47S | INT,INT,SUR | 3S9D_A_B,3SE3_B_C... | 5E-10 | 6.9E-10 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 1E+07 | 1E+07 | 5E-03 | 6.9E-03 | None | None | None | None | SP | |||
| 3QIB_ABP_CD | AA61G | AA61G | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 2.48E-05 | 5.5E-06 | I-Ek plus MCC peptide | 2B4 TCR | 298 | 2.6E+03 | 4E+03 | 6.44E-02 | 2.2E-02 | None | None | None | None | SPR | ||
| 3QIB_ABP_CD | AA64G | AA64G | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.54E-05 | 5.5E-06 | I-Ek plus MCC peptide | 2B4 TCR | 298 | 3.2E+03 | 4E+03 | 4.92E-02 | 2.2E-02 | None | None | None | None | SPR | ||
| 2J8U_ABC_EF | AA66K | AA66K | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 9.3E-06 | 3.18E-05 | HLA-A2 plus P1049 peptide | AHIII TCR | 298(assumed) | 3.1E+04 | 4.7E+03 | 2.7E-01 | 1.5E-01 | None | None | None | None | SPR | ||
| 2J8U_ABC_EF | AA66K | AA66K | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1E-06 | 7E-06 | HLA-A2 plus P1049 peptide | AHIII TCR | 298 | -3.90 | -0.60 | 14.80 | 21.10 | ITC | ||||||
| 3QIB_ABP_CD | AA68G | AA68G | RIM | TCR/pMHC | TCR/pMHC,1JCK_A_B | 2.29E-05 | 5.5E-06 | I-Ek plus MCC peptide | 2B4 TCR | 298 | 2.78E+03 | 4E+03 | 6.38E-02 | 2.2E-02 | None | None | None | None | SPR | ||
| 1AO7_ABC_DE | AA69G | AA69G | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 3.08E-05 | 4.19E-06 | HLA-A2 plus tax peptide | A6 TCR | 298 | None | None | None | None | SPR | ||||||
| 1AO7_ABC_DE | AA69G | AA69G | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 9.6E-06 | 9.1E-07 | HLA-A2 plus tax peptide | A6 TCR | 298 | 5.5E+04 | 1.1E+05 | 6.82E-01 | 9.3E-02 | None | None | None | None | SPR |