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RCSB
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7085 records found
| PDB Code | Mutation Pdb▲ | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3HFM_HL_Y | YH53L | YH53L | COR | AB/AG | AB/AG | 9.09E-09 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -19.60 | -21.90 | -27.90 | -32.60 | ITC | ||||||
| 3HFM_HL_Y | YH53W | YH53W | COR | AB/AG | AB/AG | 7.69E-09 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -23.60 | -21.90 | -40.80 | -32.60 | ITC | ||||||
| 1BJ1_HL_VW | YH54A | YH54A | RIM | AB/AG | AB/AG | 3.2E-08 | 3.4E-09 | Fab-12 | VEGF | 298(assumed) | None | None | None | None | SPR | ||||||
| 1BJ1_HL_VW | YH54W | YH54W | RIM | AB/AG | AB/AG | 2.3E-09 | 2.9E-09 | Fab-12 | VEGF | 298 | 3.8E+04 | 4.1E+04 | 8.6E-05 | 1.2E-04 | None | None | None | None | SPR | ||
| 4OZG_ABJ_GH | YH55F | YH46F | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.3E-06 | 1.58E-05 | HLA-DQ plus gliadin-alpha2 peptide | D2 TCR | 293 | None | None | None | None | SPR | ||||||
| 1JRH_LH_I | YH58A | YH60A | COR | AB/AG | AB/AG | 1E-07 | 1.2E-08 | mAbs A6 | Interferon gamma receptor | 298 | None | None | None | None | SPR | ||||||
| 3HFM_HL_Y | YH58A | YH58A | COR | AB/AG | AB/AG | 3.85E-08 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -17.30 | -21.90 | -23.00 | -32.60 | ITC | ||||||
| 1MHP_HL_A | YH58E | YH58E | COR | AB/AG | AB/AG | 2.83E-07 | 8.5E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
| 1MHP_HL_A | YH58E,HH56N | YH58E,HH56N | COR,COR | AB/AG | AB/AG | n.b. | 8.5E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
| 3HFM_HL_Y | YH58F | YH58F | COR | AB/AG | AB/AG | 4.35E-09 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -20.40 | -21.90 | -29.00 | -32.60 | ITC |