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PDBe
RCSB
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7085 records found
| PDB Code | Mutation Pdb▲ | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3HFM_HL_Y | YH58L | YH58L | COR | AB/AG | AB/AG | 2.94E-08 | 2.38E-09 | HyHEL-10 | HEW Lysozyme | 303 | -14.90 | -21.90 | -14.80 | -32.60 | ITC | ||||||
| 1MHP_HL_A | YH58Q | YH58Q | COR | AB/AG | AB/AG | 2.83E-07 | 8.5E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
| 1MHP_HL_A | YH58Q,HH56N | YH58Q,HH56N | COR,COR | AB/AG | AB/AG | n.b. | 8.5E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
| 1MHP_HL_A | YH58W | YH58W | COR | AB/AG | AB/AG | 3.4E-08 | 8.5E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
| 3NGB_HL_G | YH59A | YH60A | SUP | AB/AG | AB/AG | 5.47E-08 | 2.2E-08 | VRC01 fab | gp120 | 303 | None | None | None | None | SPR | ||||||
| 3SE8_HL_G | YH59A | YH60A | SUP | AB/AG | AB/AG | 2.61E-07 | 6.3E-08 | VRC03 Fab | gp120 | 303 | None | None | None | None | SPR | ||||||
| 1MHP_HL_A | YH59E | YH59E | SUP | AB/AG | AB/AG | 2.13E-08 | 8.5E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
| 3NGB_HL_G | YH74A | YH75A | RIM | AB/AG | AB/AG | 1.58E-08 | 2.2E-08 | VRC01 fab | gp120 | 303 | None | None | None | None | SPR | ||||||
| 3NGB_HL_G | YH74S | YH75S | RIM | AB/AG | AB/AG | 1.01E-08 | 5.76E-09 | VRC01 fab | gp120 | 298 | 3.4E+04 | 3.83E+04 | 3.43E-04 | 2.2E-04 | None | None | None | None | SPR | ||
| 4I77_HL_Z | YH97A | YH100A | RIM | AB/AG | AB/AG | <1E-11 | <1E-11 | Lebrikizumab fab | Interleukin-13 | 298 | None | None | None | None | SPR |