SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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>
<=
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in
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<=
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not in
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not in
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<
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<=
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starts with
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not in
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<
>
<=
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=
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<
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<=
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=
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=
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<
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=
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<
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb▲
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3SGB_E_I
YI20F
YI14F
COR
Pr/PI
Pr/PI
2.38E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20G
YI17G
COR
Pr/PI
Pr/PI
1.12E-09
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20G
YI20G
COR
Pr/PI
Pr/PI
1.92E-07
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20G
YI15G
COR
Pr/PI
Pr/PI
1.45E-06
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI20G
YI14G
COR
Pr/PI
Pr/PI
2.17E-09
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20H
YI17H
COR
Pr/PI
Pr/PI
7.69E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20H
YI20H
COR
Pr/PI
Pr/PI
9.09E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20H
YI15H
COR
Pr/PI
Pr/PI
1.03E-08
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI20H
YI14H
COR
Pr/PI
Pr/PI
3.23E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20H
YI17H
COR
Pr/PI
Pr/PI
5.88E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
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