SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
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!=
<
>
<=
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starts with
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in
not in
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!=
<
>
<=
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starts with
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not in
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<
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starts with
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in
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>
<=
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<=
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not in
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not in
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not in
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<=
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starts with
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not in
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<
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<=
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starts with
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in
not in
=
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
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<
>
<=
>=
=
!=
<
>
<=
>=
=
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<
>
<=
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=
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<
>
<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb▲
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3SGB_E_I
YI20K
YI14K
COR
Pr/PI
Pr/PI
5.88E-09
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20L
YI17L
COR
Pr/PI
Pr/PI
1.67E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20L
YI20L
COR
Pr/PI
Pr/PI
1.67E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20L
YI15L
COR
Pr/PI
Pr/PI
2.27E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI20L
YI14L
COR
Pr/PI
Pr/PI
2.56E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20M
YI17M
COR
Pr/PI
Pr/PI
4.17E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20M
YI20M
COR
Pr/PI
Pr/PI
1.89E-08
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20M
YI15M
COR
Pr/PI
Pr/PI
5.88E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI20M
YI14M
COR
Pr/PI
Pr/PI
5.26E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20N
YI17N
COR
Pr/PI
Pr/PI
8.33E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
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