SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
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starts with
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in
not in
=
!=
<
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<=
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starts with
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<
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<=
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starts with
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in
not in
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!=
<
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<=
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starts with
contains
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not in
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!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.▲
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3SGB_E_I
EI10D,AI15V,TI17S...
EI4D,AI9V,TI11S,R...
RIM,COR,COR,RIM,S...
Pr/PI
Pr/PI
4.76E-09
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15V,TI17S,RI21M...
AI9V,TI11S,RI15M,...
COR,COR,RIM,SUR,R...
Pr/PI
Pr/PI
3.45E-08
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI10D,YI11H,TI17L...
EI4D,YI5H,TI11L,L...
RIM,INT,COR,COR,C...
Pr/PI
Pr/PI
5E-06
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
EI10D,YI11H,TI17L...
EI4D,YI5H,TI11L,L...
RIM,INT,COR,COR,C...
Pr/PI
Pr/PI
5.26E-06
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M
LI12M
COR
Pr/PI
Pr/PI
4E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M,TI49N,KI55T
LI12M,TI43N,KI49T
COR,SUR,SUR
Pr/PI
Pr/PI
2.86E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI28S,GI32A
NI22S,GI26A
SUR,COR
Pr/PI
Pr/PI
1.69E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15D,GI32A
AI9D,GI26A
COR,COR
Pr/PI
Pr/PI
1.11E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15D,GI32A,NI33S
AI9D,GI26A,NI27S
COR,COR,SUP
Pr/PI
Pr/PI
7.14E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
GI32A
GI26A
COR
Pr/PI
Pr/PI
1.79E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
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