SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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!=
<
>
<=
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not in
=
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<
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<=
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starts with
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in
not in
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<
>
<=
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starts with
contains
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not in
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<
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starts with
contains
in
not in
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
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<
>
<=
>=
=
!=
<
>
<=
>=
=
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<
>
<=
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=
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<
>
<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.▲
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3SGB_E_I
LI18M,TI30S,GI32D
LI12M,TI24S,GI26D
COR,SUR,COR
Pr/PI
Pr/PI
9.09E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18I,GI32D
LI12I,GI26D
COR,COR
Pr/PI
Pr/PI
3.45E-07
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15D,LI18A,YI20D
AI9D,LI12A,YI14D
COR,COR,COR
Pr/PI
Pr/PI
3.03E-07
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M,SI51N,HI52R...
LI12M,SI45N,HI46R...
COR,SUR,SUR,SUR
Pr/PI
Pr/PI
2.63E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M,HI52R
LI12M,HI46R
COR,SUR
Pr/PI
Pr/PI
4.17E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M,HI52R,KI55E
LI12M,HI46R,KI49E
COR,SUR,SUR
Pr/PI
Pr/PI
1.47E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M,SI51N
LI12M,SI45N
COR,SUR
Pr/PI
Pr/PI
3.85E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI11H,YI20D,TI30I...
YI5H,YI14D,TI24I,...
INT,COR,SUR,COR,R...
Pr/PI
Pr/PI
2.33E-07
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI20H
YI14H
COR
Pr/PI
Pr/PI
1.92E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
LI18M,YI20Q
LI12M,YI14Q
COR,COR
Pr/PI
Pr/PI
1.05E-08
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
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