SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)▲	Kon Mut	Kon Wt	Koff Mut	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
1N8Z_AB_C	YB109V	YB109V	INT	AB/AG	AB/AG	5.1E-10	3.5E-10	Herceptin	erbB-2	310	1.2E+06	1E+06	6.2E-04	3.5E-04	None	None	None	None	SPR
1N8Z_AB_C	NA30S,HA91F,YA92W...	NA30S,HA91F,YA92W...	COR,SUP,COR,COR,R...	AB/AG	AB/AG	3.8E-10	3.5E-10	Herceptin	erbB-2	310	2.2E+06	1E+06	8.4E-04	3.5E-04	None	None	None	None	SPR
5DWU_HL_AB	IB338A	IB84A	INT	AB/AG	AB/AG	n.b	1E-10	CSL311 fab	Cytokine receptor common subunit beta	310					None	None	None	None	SPR
5DWU_HL_AB	FA103A	FA78A	SUP	AB/AG	AB/AG	n.b	1E-10	CSL311 fab	Cytokine receptor common subunit beta	310					None	None	None	None	SPR
5DWU_HL_AB	QB339A	QB85A	INT	AB/AG	AB/AG	n.b	1E-10	CSL311 fab	Cytokine receptor common subunit beta	310					None	None	None	None	SPR
5DWU_HL_AB	IB424A	IB169A	INT	AB/AG	AB/AG	n.b	1E-10	CSL311 fab	Cytokine receptor common subunit beta	310					None	None	None	None	SPR
1U7F_B_AC	RB378A	RB65A	RIM		1U7F_B_AC	1.09E-06	5.8E-08	Smad4	Smad3	310					-8.50	-7.50	0.01	8.80	ITC
1U7F_B_AC	DB493A	DB140A	COR		1U7F_B_AC	5.29E-06	5.8E-08	Smad4	Smad3	310					-3.80	-7.50	11.90	8.80	ITC
1LFD_A_B	IA18A	IA5A	RIM		1LFD_A_B,4G0N_A_B...	2.63E-05	1.21E-06	RalGDS-RBD	H-Ras1	310					None	None	None	None	IAFL
1LFD_A_B	RA20A	RA7A	RIM		1LFD_A_B,4G0N_A_B...	5.92E-05	1.21E-06	RalGDS-RBD	H-Ras1	310					None	None	None	None	IAFL