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RCSB
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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut▼ | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1GUA_A_B | VB69A,EA37A | VB14A,EA37A | COR,COR | 1GUA_A_B,1C1Y_A_B... | 8.7E-06 | 4.93E-07 | Rap1a | Raf-RBD | 298 | -3.30 | -5.60 | 12.7516778523 | 10.067114094 | ITC | |||||||
4G0N_A_B | EA31A | EA31A | RIM | 4G0N_A_B,3KUD_A_B... | 8.33E-07 | 8E-08 | H-Ras1 | Raf-RBD | 298 | -3.30 | -5.20 | 16.7785234899 | 15.100671141 | ITC | |||||||
3M62_A_B | RA92A | RA98A | RIM | 3M62_A_B,3M63_A_B | 2.65E-07 | 7E-08 | Ubiquitin conjugation factor E4 | Rad23 | 298 | -3.40 | -17.30 | 18.80 | -24.80 | ITC | |||||||
3UII_A_P | KA62Y,HA80W | KA58Y,HA76W | RIM,RIM | 3UII_A_P,3UIG_A_P... | 1.06E-05 | 1E-05 | Survivin | Histone H3(1-10) peptide | 298 | -3.52 | -5.51 | 10.90 | 4.38 | ITC | |||||||
1BRS_A_D | EA73F,DD35A | EA71F,DD35A | SUP,COR | 1BRS_A_D,1B2U_A_D... | 5E-10 | 1E-14 | Barnase | Barstar | 298 | -3.70 | -19.30 | 29.90 | -1.01 | ITC | |||||||
1U7F_B_AC | DB493A | DB140A | COR | 1U7F_B_AC | 5.29E-06 | 5.8E-08 | Smad4 | Smad3 | 310 | -3.80 | -7.50 | 11.90 | 8.80 | ITC | |||||||
1GUA_A_B | KB65A | KB10A | RIM | 1GUA_A_B,1C1Y_A_B... | 2.51E-07 | 4.93E-07 | Rap1a | Raf-RBD | 298 | -3.80 | -5.60 | 17.4496644295 | 10.067114094 | ITC | |||||||
4G0N_A_B | DA33A | DA33A | RIM | 4G0N_A_B,3KUD_A_B... | 2.56E-07 | 8E-08 | H-Ras1 | Raf-RBD | 298 | -3.80 | -5.20 | 17.4496644295 | 15.100671141 | ITC | |||||||
2GOX_A_B | RB131A | RB31A | COR | 2GOX_A_B,3D5S_A_C... | 2.6E-08 | 2E-09 | Complement C3d | Fibrinogen-binding protein Efb-C | 298 | -3.90 | -8.50 | 21.50 | 11.40 | ITC | |||||||
2J8U_ABC_EF | AA66K | AA66K | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1E-06 | 7E-06 | HLA-A2 plus P1049 peptide | AHIII TCR | 298 | -3.90 | -0.60 | 14.80 | 21.10 | ITC |