SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Dh Mut▼	Dh Wt	Ds Mut	Ds Wt	Method
3M63_A_B	GB10F,QB11K,SB67Q...	GB8F,QB9K,SB65Q,H...	RIM,SUR,RIM,COR,COR		3M63_A_B,3M62_A_B...	2.4E-07	1.75E-07	Ubiquitin conjugation factor E4	DSK2	298	-2.50	-10.10	21.80	-2.68	ITC
2REX_A_B	YB114F	YB97F	RIM		2REX_A_B,3Q3J_A_B...	5.5E-06	5.5E-06	Plexin-B1	Rnd-1	298	-2.50	-6.70	14.00	1.68	ITC
2KSO_A_B	KA23D,DB52K	KA10D,DB25K	COR,RIM		2KSO_A_B	1E-05	5.2E-06	Ephrin type-A receptor 2 SAM	SHIP2 SAM	298(assumed)	-2.50	-2.50	14.4295302013	15.7718120805	ITC
1CBW_FGH_I	VI34A	VI34A	RIM	Pr/PI	Pr/PI	1.42E-08	1.42E-08	Bovine alpha-chymotrypsin	BPTI	295	-2.70	2.50	27.10	44.70	ITC
1GUA_A_B	EA37A	EA37A	COR		1GUA_A_B,1C1Y_A_B...	4.43E-06	4.93E-07	Rap1a	Raf-RBD	298	-2.70	-5.60	15.4362416107	10.067114094	ITC
4G0N_A_B	KB84A,EA37A	KB31A,EA37A	RIM,RIM		4G0N_A_B,3KUD_A_B...	2.44E-05	8.02E-08	H-Ras1	Raf-RBD	308	-2.80	-8.60	12.012987013	4.55	ITC
1GUA_A_B	NB64A	NB9A	RIM		1GUA_A_B,1C1Y_A_B...	2.51E-07	4.93E-07	Rap1a	Raf-RBD	298	-2.90	-5.60	20.8053691275	10.067114094	ITC
1BRS_A_D	EA73A,DD35A	EA71A,DD35A	SUP,COR		1BRS_A_D,1B2U_A_D...	5.26E-10	1E-14	Barnase	Barstar	298	-3.00	-19.30	32.20	-1.01	ITC
1JTG_A_B	SB71A	SB71A	SUP		1XXM_A_C,1S0W_A_C...	3.01E-10	1.11E-10	TEM-1 beta-lactamase	BLIP	303	-3.20	-7.40	33.00330033	21.10	ITC
4G0N_A_B	RB67A	RB14A	RIM		4G0N_A_B,3KUD_A_B...	1E-06	8E-08	H-Ras1	Raf-RBD	298	-3.20	-5.20	16.7785234899	15.100671141	ITC