SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Dh Mut	Dh Wt	Ds Mut▼	Ds Wt	Method
2KSO_A_B	KA23E,EB54K	KA10E,EB27K	COR,RIM		2KSO_A_B	1.54E-05	5.2E-06	Ephrin type-A receptor 2 SAM	SHIP2 SAM	298(assumed)	-2.00	-2.50	15.4362416107	15.7718120805	ITC
4G0N_A_B	VB88A	VB35A	COR		4G0N_A_B,3KUD_A_B...	6.67E-08	8E-08	H-Ras1	Raf-RBD	298	-5.30	-5.20	15.1006711409	15.100671141	ITC
1BRS_A_D	EA73W,DD39A	EA71W,DD39A	SUP,COR		1BRS_A_D,1B2U_A_D...	7.69E-10	1E-14	Barnase	Barstar	298	-7.90	-19.30	15.10	-1.01	ITC
2J8U_ABC_EF	AA66K	AA66K	SUP	TCR/pMHC	TCR/pMHC,1JCK_A_B	1E-06	7E-06	HLA-A2 plus P1049 peptide	AHIII TCR	298	-3.90	-0.60	14.80	21.10	ITC
4G0N_A_B	NB64A	NB11A	RIM		4G0N_A_B,3KUD_A_B...	1.67E-07	8E-08	H-Ras1	Raf-RBD	298	-5.00	-5.20	14.4295302013	15.100671141	ITC
2KSO_A_B	KA23D,DB52K	KA10D,DB25K	COR,RIM		2KSO_A_B	1E-05	5.2E-06	Ephrin type-A receptor 2 SAM	SHIP2 SAM	298(assumed)	-2.50	-2.50	14.4295302013	15.7718120805	ITC
1GUA_A_B	QB66A	QB11A	COR		1GUA_A_B,1C1Y_A_B...	5.84E-07	4.93E-07	Rap1a	Raf-RBD	298	-4.30	-5.60	14.0939597315	10.067114094	ITC
2REX_A_B	YB114F	YB97F	RIM		2REX_A_B,3Q3J_A_B...	5.5E-06	5.5E-06	Plexin-B1	Rnd-1	298	-2.50	-6.70	14.00	1.68	ITC
1GUA_A_B	VB69A	VB14A	COR		1GUA_A_B,1C1Y_A_B...	5.84E-07	4.93E-07	Rap1a	Raf-RBD	298	-4.50	-5.60	13.4228187919	10.067114094	ITC
2C0L_A_B	QA586R	QA239R	INT		2C0L_A_B,3R9A_AC_B	1.34E-06	1.09E-07	TRP region of PEX5	Sterol carrier protein 2	305	-4.16	-10.10	13.40	-0.962	ITC