SKEMPI v2.0

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7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Proteins	Affinity Mut	Affinity Wt	Protein 1	Protein 2	T (ºK)	Dh Mut	Dh Wt	Ds Mut▼	Ds Wt	Method
4G0N_A_B	QB66A,RA41A	QB13A,RA41A	COR,COR	4G0N_A_B,3KUD_A_B...	6.71E-07	8.02E-08	H-Ras1	Raf-RBD	308	-6.10	-8.60	8.4415584416	4.55	ITC
3M62_A_B	QB52A	QB50A	RIM	3M62_A_B,3M63_A_B	4.15E-07	7E-08	Ubiquitin conjugation factor E4	Rad23	298	-6.20	-17.30	8.39	-24.80	ITC
2DVW_A_B	RA41A,KA116A	RA39A,KA114A	SUP,COR	2DVW_A_B,4HRN_A_D...	3.63E-06	6.73E-08	Gankyrin	S6 ATPase	298	-4.90	-28.70	8.389261745	-63.76	ITC
2C0L_A_B	NA382A	NA48A	INT	2C0L_A_B,3R9A_AC_B	3.48E-07	1.09E-07	TRP region of PEX5	Sterol carrier protein 2	305	-6.52	-10.10	8.38	-0.962	ITC
4G0N_A_B	DA33A	DA33A	RIM	4G0N_A_B,3KUD_A_B...	4.84E-07	8.02E-08	H-Ras1	Raf-RBD	308	-6.50	-8.60	7.7922077922	4.55	ITC
4G0N_A_B	VA45A	VA45A	SUR	4G0N_A_B,3KUD_A_B...	4.91E-08	8.02E-08	H-Ras1	Raf-RBD	308	-7.90	-8.60	7.7922077922	4.55	ITC
4G0N_A_B	TB68A,EA37A	TB15A,EA37A	SUP,RIM	4G0N_A_B,3KUD_A_B...	9.16E-06	8.02E-08	H-Ras1	Raf-RBD	308	-4.70	-8.60	7.7922077922	4.55	ITC
1GUA_A_B	KB84A	KB29A	RIM	1GUA_A_B,1C1Y_A_B...	1.44E-05	4.93E-07	Rap1a	Raf-RBD	298	-4.30	-5.60	7.7181208054	10.067114094	ITC
4G0N_A_B	NB64A	NB11A	RIM	4G0N_A_B,3KUD_A_B...	9.45E-08	8.02E-08	H-Ras1	Raf-RBD	308	-7.60	-8.60	7.4675324675	4.55	ITC
4G0N_A_B	RA41A	RA41A	COR	4G0N_A_B,3KUD_A_B...	3.01E-08	8.02E-08	H-Ras1	Raf-RBD	308	-8.30	-8.60	7.4675324675	4.55	ITC