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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut▼ | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1JTG_A_B | SB39A | SB39A | SUP | 1XXM_A_C,1S0W_A_C... | 2.01E-10 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 293 | 2.70 | -7.40 | 53.5836177474 | 21.10 | ITC | |||||||
1JTG_A_B | HB148A | HB148A | SUP | 1XXM_A_C,1S0W_A_C... | 5E-08 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 285 | 5.60 | -7.40 | 53.00 | 21.10 | ITC | |||||||
1JTG_A_B | FB142A | FB142A | COR | 1XXM_A_C,1S0W_A_C... | 3.85E-08 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 281 | 5.30 | -7.40 | 52.90 | 21.10 | ITC | |||||||
1JTG_A_B | YB53A | YB53A | SUP | 1XXM_A_C,1S0W_A_C... | 7.14E-08 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 281 | 5.10 | -7.40 | 50.80 | 21.10 | ITC | |||||||
2HLE_A_B | KA149Q | KA141Q | COR | 2HLE_A_B,4L0P_A_B | 2E-08 | 4E-08 | Ephrin type-B receptor 4 | Ephrin-B2 | 298 | 3.70 | 3.30 | 48.30 | 44.90 | ITC | |||||||
1AO7_ABC_DE | YC5F | YC5F | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.2E-06 | 9E-07 | HLA-A2 plus tax peptide | A6 TCR | 277 | 5.90 | 4.40 | 48.00 | 44.00 | ITC | ||||||
1JTG_A_B | WB112A | WB112A | COR | 1XXM_A_C,1S0W_A_C... | 1.56E-08 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 279 | 3.30 | -7.40 | 47.50 | 21.10 | ITC | |||||||
1CBW_FGH_I | RI39A | RI39A | RIM | Pr/PI | Pr/PI | 1.99E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 3.10 | 2.50 | 46.10 | 44.70 | ITC | ||||||
1CBW_FGH_I | GI37A | GI37A | COR | Pr/PI | Pr/PI | 5.49E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 3.60 | 2.50 | 45.70 | 44.70 | ITC | ||||||
1CBW_FGH_I | PI13A | PI13A | COR | Pr/PI | Pr/PI | 1.2E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.60 | 2.50 | 45.40 | 44.70 | ITC |