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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut▼ | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1JTG_A_B | KB74A | KB74A | SUP | 1XXM_A_C,1S0W_A_C... | 6.25E-08 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 279 | 3.50 | -7.40 | 45.30 | 21.10 | ITC | |||||||
1CBW_FGH_I | TI11A | TI11A | COR | Pr/PI | Pr/PI | 1.99E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.80 | 2.50 | 45.10 | 44.70 | ITC | ||||||
3R9A_AC_B | AA328W | AA323W | RIM | 3R9A_AC_B,2C0L_A_B | 6.2E-06 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 6.31 | 3.80 | 45.00 | 37.70 | ITC | |||||||
1CBW_FGH_I | RI17A | RI17A | COR | Pr/PI | Pr/PI | 3.31E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.80 | 2.50 | 44.40 | 44.70 | ITC | ||||||
1CBW_FGH_I | II19A | II19A | RIM | Pr/PI | Pr/PI | 1.68E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.50 | 2.50 | 44.40 | 44.70 | ITC | ||||||
3QFJ_ABC_DE | FC5Y | FC5Y | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 9E-07 | 1.2E-06 | HLA-A2 plus tax peptide | A6 TCR | 277 | 4.40 | 5.90 | 44.00 | 48.00 | ITC | ||||||
1CBW_FGH_I | RI20A | RI20A | INT | Pr/PI | Pr/PI | 2.36E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.50 | 2.50 | 43.70 | 44.70 | ITC | ||||||
1CBW_FGH_I | KI46A | KI46A | SUR | Pr/PI | Pr/PI | 1.68E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 2.30 | 2.50 | 43.70 | 44.70 | ITC | ||||||
2HLE_A_B | LA95R | LA87R | SUP | 2HLE_A_B,4L0P_A_B | 1.9E-06 | 4E-08 | Ephrin type-B receptor 4 | Ephrin-B2 | 298 | 5.20 | 3.30 | 43.60 | 44.90 | ITC | |||||||
1CBW_FGH_I | GI36A | GI36A | SUP | Pr/PI | Pr/PI | 6.5E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 3.00 | 2.50 | 43.40 | 44.70 | ITC |