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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut▼ | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3R9A_AC_B | YA330W | YA325W | SUP | 3R9A_AC_B,2C0L_A_B | 7.9E-06 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 5.59 | 3.80 | 42.20 | 37.70 | ITC | |||||||
1CBW_FGH_I | KI15A | KI15A | COR | Pr/PI | Pr/PI | 4.17E-07 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 3.40 | 2.50 | 41.00 | 44.70 | ITC | ||||||
3R9A_AC_B | GA170R | GA165R | INT | 3R9A_AC_B,2C0L_A_B | 3.8E-06 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 4.52 | 3.80 | 39.90 | 37.70 | ITC | |||||||
1CBW_FGH_I | YI35A | YI35A | INT | Pr/PI | Pr/PI | 5.49E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | 1.80 | 2.50 | 39.60 | 44.70 | ITC | ||||||
1JTG_A_B | YB50A | YB50A | COR | 1XXM_A_C,1S0W_A_C... | 3.1E-12 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 288 | -3.90 | -7.40 | 39.1180324956 | 21.10 | ITC | |||||||
3R9A_AC_B | VA336D | VA331D | INT | 3R9A_AC_B,2C0L_A_B | 3.5E-06 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 4.11 | 3.80 | 38.80 | 37.70 | ITC | |||||||
3R9A_AC_B | YA330A | YA325A | SUP | 3R9A_AC_B,2C0L_A_B | 1.94E-05 | 3.5E-06 | Alanine-glyoxylate aminotransferase | PEX5P | 298 | 3.97 | 3.80 | 35.00 | 37.70 | ITC | |||||||
1JTG_A_B | SB71A | SB71A | SUP | 1XXM_A_C,1S0W_A_C... | 3.01E-10 | 1.11E-10 | TEM-1 beta-lactamase | BLIP | 303 | -3.20 | -7.40 | 33.00330033 | 21.10 | ITC | |||||||
1BRS_A_D | EA73A,DD35A | EA71A,DD35A | SUP,COR | 1BRS_A_D,1B2U_A_D... | 5.26E-10 | 1E-14 | Barnase | Barstar | 298 | -3.00 | -19.30 | 32.20 | -1.01 | ITC | |||||||
1CBW_FGH_I | GI12A | GI12A | SUP | Pr/PI | Pr/PI | 3.92E-08 | 1.42E-08 | Bovine alpha-chymotrypsin | BPTI | 295 | -0.60 | 2.50 | 32.20 | 44.70 | ITC |