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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type▼ | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2VLR_ABC_DE | AE99S | AE95S | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.2E-06 | 4.9E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | 3.1E+04 | 5.9E+04 | 1.6E-01 | 2.9E-01 | None | None | None | None | SPR | ||
1OGA_ABC_DE | DE32A | DE28A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 7.4E-05 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | DE32S | DE28S | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | >2E-04 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | QE52A | QE48A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | >2E-04 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | QE52E | QE48E | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | >2E-04 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | IE53A | IE49A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | >2E-04 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | IE53G | IE49G | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | >2E-04 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | IE53N | IE49N | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | >2E-04 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | None | None | None | None | SPR | ||||||
1OGA_ABC_DE | IE53V | IE49V | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 7.3E-06 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | 1.71E+04 | 3.1E+04 | 1.3E-01 | 1.6E-01 | None | None | None | None | SPR | ||
1OGA_ABC_DE | IE53L | IE49L | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.7E-05 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | 7E+03 | 3.1E+04 | 4E-01 | 1.6E-01 | None | None | None | None | SPR |