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PDBe
RCSB
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7085 records found
| PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type▼ | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1OGA_ABC_DE | SD31A | SD29A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.5E-05 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | 1.3E+04 | 3.1E+04 | 2E-01 | 1.6E-01 | None | None | None | None | SPR | ||
| 1OGA_ABC_DE | SD32A | SD30A | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 3E-05 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | 1.5E+04 | 3.1E+04 | 4.6E-01 | 1.6E-01 | None | None | None | None | SPR | ||
| 1OGA_ABC_DE | QD34A | QD32A | INT | TCR/pMHC | TCR/pMHC,1JCK_A_B | 2.7E-05 | 5.2E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | 3.8E+04 | 3.1E+04 | 1.03E+00 | 1.6E-01 | None | None | None | None | SPR | ||
| 2VLR_ABC_DE | AE99S | AE95S | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.24E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -23.00 | -18.00 | -50.30 | -33.50 | ITC | ||||||
| 1OGA_ABC_DE | IE53V | IE49V | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 7.35E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -22.00 | -23.00 | -50.30 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | NE55A | NE51A | RIM | TCR/pMHC | TCR/pMHC,1JCK_A_B | 3.36E-05 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -18.00 | -23.00 | -40.20 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | DE56A | DE52A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 6.21E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -24.00 | -23.00 | -57.00 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | QE58A | QE54A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.22E-05 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -18.00 | -23.00 | -36.90 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | QE58E | QE54E | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.24E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -20.00 | -23.00 | -43.60 | -50.30 | ITC | ||||||
| 1OGA_ABC_DE | SE99A | SE95A | SUP | TCR/pMHC | TCR/pMHC,1JCK_A_B | 5.24E-06 | 5.24E-06 | HLA-A2 plus flu peptide | JM22 TCR | 298 | -18.00 | -23.00 | -33.50 | -50.30 | ITC |