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RCSB
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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut▼ | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2FTL_E_I | VI34A | VI34A | COR | Pr/PI | Pr/PI | <5E-11 | 5E-14 | Bovine trypsin | BPTI | 295 | 7E+05 | 9.9E+05 | <7E-05 | 5E-08 | None | None | None | None | IASP | ||
1BJ1_HL_VW | HH101Y,YH103W,SH105T | HH101Y,YH103W,SH105T | COR,RIM,RIM | AB/AG | AB/AG | <5E-10 | 2.9E-09 | Fab-12 | VEGF | 298 | 1.1E+04 | 4.1E+04 | <6E-06 | 1.2E-04 | None | None | None | None | SPR | ||
1CZ8_HL_VW | LL4M,DH28T,HH31N,... | LL4M,DH28T,HH31N,... | INT,SUR,COR,RIM | AB/AG | AB/AG | <5E-10 | <1.4E-10 | Fab-12 | VEGF | 298 | 1.1E+04 | 4.1E+04 | <6E-06 | 1.2E-04 | None | None | None | None | SPR | ||
1BJ1_HL_VW | ML4L,TH28D,NH31H,... | ML4L,TH28D,NH31H,... | INT,SUR,COR,COR,RIM | AB/AG | AB/AG | <1.4E-10 | 2.9E-09 | Fab-12 | VEGF | 298 | 3.6E+04 | 4.1E+04 | <5E-06 | 1.2E-04 | None | None | None | None | SPR | ||
1BJ1_HL_VW | TH28D,NH31H,HH101... | TH28D,NH31H,HH101... | SUR,COR,COR,RIM | AB/AG | AB/AG | <1.5E-10 | 2.9E-09 | Fab-12 | VEGF | 298 | 3.5E+04 | 4.1E+04 | <5E-06 | 1.2E-04 | None | None | None | None | SPR | ||
1CZ8_HL_VW | LL4M | LL4M | INT | AB/AG | AB/AG | <1.5E-10 | <1.4E-10 | Fab-12 | VEGF | 298 | 3.5E+04 | 4.1E+04 | <5E-06 | 1.2E-04 | None | None | None | None | SPR | ||
2FTL_E_I | RI17A | RI17A | COR | Pr/PI | Pr/PI | <5E-11 | 5E-14 | Bovine trypsin | BPTI | 295 | 1.1E+06 | 9.9E+05 | <5.6E-05 | 5E-08 | None | None | None | None | IASP | ||
2FTL_E_I | RI20A | RI20A | SUP | Pr/PI | Pr/PI | <5E-11 | 5E-14 | Bovine trypsin | BPTI | 295 | 1.1E+06 | 9.9E+05 | <5.6E-05 | 5E-08 | None | None | None | None | IASP | ||
2FTL_E_I | II19A | II19A | RIM | Pr/PI | Pr/PI | <5E-11 | 5E-14 | Bovine trypsin | BPTI | 295 | 5.5E+05 | 9.9E+05 | <5.5E-05 | 5E-08 | None | None | None | None | IASP | ||
1BJ1_HL_VW | HH101Y,SH105T | HH101Y,SH105T | COR,RIM | AB/AG | AB/AG | <3E-10 | 2.9E-09 | Fab-12 | VEGF | 298 | 1.3E+04 | 4.1E+04 | <4E-06 | 1.2E-04 | None | None | None | None | SPR |