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PDBe
RCSB
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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut▼ | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1CZ8_HL_VW | LL4M,DH28T,HH31N,... | LL4M,DH28T,HH31N,... | INT,SUR,COR,RIM,R... | AB/AG | AB/AG | 1.4E-09 | <1.4E-10 | Fab-12 | VEGF | 298 | 5.7E+03 | 4.1E+04 | 8E-06 | 1.2E-04 | None | None | None | None | SPR | ||
1BRS_A_D | WA35F | WA33F | SUP | 1BRS_A_D,1B2U_A_D... | 1.4E-13 | 1.3E-14 | Barnase | Barstar | 298 | 5.6E+08 | 6E+08 | 8E-05 | 8E-06 | None | None | None | None | SFFL | |||
1JTG_A_B | EA110V,EA168G | EA85V,EA143G | COR,RIM | 1XXM_A_C,1S0W_A_C... | 8E-11 | 2.8E-10 | TEM-1 beta-lactamase | BLIP | 298(assumed) | 1.11E+06 | 3E+05 | 8E-05 | 8.5E-05 | None | None | None | None | SPR,SFFL | |||
1Z7X_W_X | WW261A | WW261A | COR | 1Z7X_W_X,1A4Y_A_B | 4.1E-13 | 4.3E-14 | Ribonuclease inhibitor | RNase A | 298 | 2E+08 | 2.8E+08 | 8E-05 | 1.2E-05 | None | None | None | None | SFFL | |||
3BE1_HL_A | DL27aN,PL27cA,RL2... | DL28N,PL30A,RL31K... | SUR,SUR,RIM,RIM,R... | AB/AG | AB/AG | 2E-10 | 2E-08 | bH1 Fab | erbB-2 | 303 | 3.7E+05 | 1E+05 | 8E-05 | 2.1E-03 | None | None | None | None | SPR | ||
2C5D_AB_CD | WA526F,WB526F | WA238F,WB238F | INT,INT | 2C5D_A_C,4RA0_A_C... | 2.1E-08 | 4E-09 | GAS6 | Axl | 298(assumed) | 3.9E+03 | 3.8E+04 | 8E-05 | 1.5E-04 | None | None | None | None | SPR | |||
3N85_A_LH | WL94Y | WL94Y | COR | AB/AG | AB/AG,3MZW_A_B | 7.4E-10 | 7.9E-10 | HER2 | Fab37 | 298(assumed) | 1.1E+06 | 1.3E+06 | 8E-04 | 9.8E-04 | None | None | None | None | SPR | ||
1FC2_C_D | QC151L | QC28L | RIM | 1FC2_C_D,1FCC_A_C... | 1.3E-09 | 6E-10 | Protein A/Z | IgG1 Fc | 298 | 5.8E+06 | 8.8E+06 | 8E-03 | 5E-03 | None | None | None | None | SPR | |||
1AO7_ABC_DE | DD26W | DD26W | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 3.39E-07 | 2.1E-06 | HLA-A2 plus tax peptide | A6 TCR | 298 | 2.44E+04 | 5.11E+04 | 8E-03 | 1.08E-01 | None | None | None | None | SPR | ||
3S9D_A_B | SA25A | SA18A | RIM | 3S9D_A_B,3SE3_B_C... | 2.6E-09 | 3E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | 3.2E+06 | 3.7E+06 | 8E-03 | 1.1E-02 | None | None | None | None | SP |