SKEMPI v2.0

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Mutations

7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Ref.	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut▼	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
1BJ1_HL_VW	HH101Y,YH103R,GH1...	HH101Y,YH103R,GH1...	COR,RIM,RIM,RIM	AB/AG	AB/AG	8E-10	2.9E-09		Fab-12	VEGF	298	1.2E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,RIM	AB/AG	AB/AG	4E-10	<1.4E-10		Fab-12	VEGF	298	2.6E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1CZ8_HL_VW	LL4M,DH28T,HH31N,...	LL4M,DH28T,HH31N,...	INT,SUR,COR,RIM,RIM	AB/AG	AB/AG	8E-10	<1.4E-10		Fab-12	VEGF	298	1.2E+04	4.1E+04	9E-06	1.2E-04	None	None	None	None	SPR
1JTG_A_B	EA110V	EA85V	COR		1XXM_A_C,1S0W_A_C...	9E-11	2.8E-10		TEM-1 beta-lactamase	BLIP	298(assumed)	6.9E+05	3E+05	9E-05	8.5E-05	None	None	None	None	SPR,SFFL
1JTG_A_B	EA171K	EA146K	RIM		1XXM_A_C,1S0W_A_C...	1E-10	2.8E-10		TEM-1 beta-lactamase	BLIP	298(assumed)	1.02E+06	3E+05	9E-05	8.5E-05	None	None	None	None	SPR,SFFL
3L5X_A_HL	NL92E,EL93S,YL94G	NL92E,EL93S,YL94G	RIM,SUR,SUR	AB/AG	AB/AG,3LB6_A_C	8.9E-11	7.54E-10		Interleukin-13	H2L6 fab	298	1.02E+06	1.25E+06	9E-05	9.4E-04	None	None	None	None	SPR
3MZW_A_B	NB6A,NB23T,SB33K,...	NB1A,NB18T,SB28K,...	RIM,SUR,SUR,SUR,S...		3MZW_A_B,1FC2_C_D...	1.6E-11	2.3E-11		Affibody ZHER2:342	erbB-2	298(assumed)	5.7E+06	4E+06	9E-05	8.8E-05	None	None	None	None	SPR
5C6T_HL_A	IA299A	IA201A	SUP	AB/AG	AB/AG	5.8E-10	1.3E-10		1G2 fab	HCMV glycoprotein B	298(assumed)	1.55E+05	2.95E+05	9E-05	3.75E-05	None	None	None	None	SPR
3HFM_HL_Y	DY101F	DY101F	COR	AB/AG	AB/AG	5E-09	7.5E-11		HyHEL-10	HEW Lysozyme	298	1.8E+05	1.49E+06	9E-04	1.12E-04	None	None	None	None	IASP
3N85_A_LH	WL91F	WL91F	SUP	AB/AG	AB/AG,3MZW_A_B	1E-09	7.9E-10		HER2	Fab37	298(assumed)	1E+06	1.3E+06	9E-04	9.8E-04	None	None	None	None	SPR

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