SKEMPI v2.0

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Mutations

7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Ref.	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut▼	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
3HFM_HL_Y	IY98A	IY98A	SUP	AB/AG	AB/AG	7E-11	7E-11		HyHEL-10	HEW Lysozyme	298	1.38E+06	1.43E+06	9.1E-05	1E-04	None	None	None	None	IASP
3MZW_A_B	NB6A,NB23T,SB33K,...	NB1A,NB18T,SB28K,...	RIM,SUR,SUR,SUR,S...		3MZW_A_B,1FC2_C_D...	1.2E-11	2.3E-11		Affibody ZHER2:342	erbB-2	298(assumed)	7.2E+06	4E+06	9.1E-05	8.8E-05	None	None	None	None	SPR
1JTD_A_B	FB209A	FB171A	COR		1JTD_A_B,1XXM_A_C...	1.97E-11	4.8E-13		TEM-1 beta-lactamase	BLIP-II	298(assumed)	4.6E+06	7.7E+06	9.1E-05	3.7E-06	None	None	None	None	IASP
1BRS_A_D	NA58A	NA56A	SUP		1BRS_A_D,1B2U_A_D...	2.5E-11	1.3E-13		Barnase	Barstar	298	3.6E+07	1.2E+08	9.1E-04	1.5E-05	None	None	None	None	SFFL
1BRS_A_D	RA83Q,WD38F	RA81Q,WD38F	COR,COR		1BRS_A_D,1B2U_A_D...	9E-10	1E-14		Barnase	Barstar	298	1E+08	3.7E+08	9.1E-02	3.73E-06	None	None	None	None	SFFL
2BNR_ABC_DE	DA61A	DA61A	SUR	TCR/pMHC	TCR/pMHC,1JCK_A_B...	2.75E-06	3.2E-06		HLA-A2 plus NY-ESO peptide	1G4 TCR	298	2.526316E+04	2.4E+04	9.1E-02	1E-01	None	None	None	None	SPR
1B41_A_B	MB33Q	MB33Q	COR		1B41_A_B,1FSS_A_B...	1.39E-09	9.4E-11		Human acetylcholinesterase	Fasciculin II	298(assumed)	6.6E+05	5.05E+06	9.17E-04	4.75E-04	None	None	None	None	IASP
1JTG_A_B	WB150A	WB150A	COR		1XXM_A_C,1S0W_A_C...	6.26E-06	4.77E-09		TEM-1 beta-lactamase	BLIP	298	2.46E+04	6.7E+04	9.08E-02	1.5E-04	None	None	None	None	SPR
3BT1_A_U	LU55A	LU55A	SUP		3BT1_A_U	3E-09	4.6E-10		Urokinase-type plasminogen activator	Urokinase plasminogen activator surface receptor	293	3.02E+05	3.98E+05	9.04E-04	1.77E-04	None	None	None	None	SPR
1BJ1_HL_VW	HH101Y,YH103I,GH1...	HH101Y,YH103I,GH1...	COR,RIM,RIM,RIM	AB/AG	AB/AG	1.4E-09	2.9E-09		Fab-12	VEGF	298	5.7E+03	4.1E+04	8E-06	1.2E-04	None	None	None	None	SPR