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7085 records found
| PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut▼ | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2WPT_A_B | NA34A | NA31A | COR | 2WPT_A_B,2VLP_A_B... | 7.9E-09 | 1.5E-08 | Colicin E2 immunity protein | Colicin E9 DNase | 298 | 8.9E+07 | 5E+07 | 7E-01 | 7.3E-01 | None | None | None | None | SFFL | |||
| 1LFD_A_B | LA23K | LA10K | INT | 1LFD_A_B,4G0N_A_B... | 1.89E-06 | 1.94E-06 | RalGDS-RBD | H-Ras1 | 298 | 8.9E+06 | 7.7E+06 | 1.68E+01 | 1.49E+01 | None | None | None | None | SFFL | |||
| 1YY9_CD_A | SD53P | SD53P | SUP | AB/AG | AB/AG | 5.21E-09 | 1.31E-09 | Cetuximab fab | Epidermal growth factor receptor | 298 | 8.9E+05 | 1.46E+06 | 4.65E-03 | 1.91E-03 | None | None | None | None | SPR | ||
| 3BT1_A_U | HU143A | HU141A | INT | 3BT1_A_U | 1.35E-09 | 4.6E-10 | Urokinase-type plasminogen activator | Urokinase plasminogen activator surface receptor | 293 | 8.9E+05 | 3.98E+05 | 1.2E-03 | 1.77E-04 | None | None | None | None | SPR | |||
| 4CVW_A_C | LC41W | LC34W | COR | 4CVW_A_C | 7.4E-11 | 4.2E-11 | Limit dextrinase | Limit dextrinase inhibitor | 298 | 8.9E+05 | 1.5E+06 | 6.5E-05 | 6.4E-05 | None | None | None | None | SPR | |||
| 1MQ8_A_B | CB299F,TB300C | CB170F,TB171C | INT,SUR | 1MQ8_A_B | 9.4E-06 | 3E-06 | Intercellular adhesion molecule I | Integrin alpha-L | 298 | 8.9E+04 | 1.33E+05 | 7.6E-01 | 4.3E-01 | None | None | None | None | SPR | |||
| 1JTG_A_B | VA216A | VA190A | COR | 1XXM_A_C,1S0W_A_C... | 8.6E-11 | 2.3E-10 | TEM-1 beta-lactamase | BLIP | 296 | 8.9E+04 | 1.08E+05 | 7.7E-06 | 2.48E-05 | None | None | None | None | SFFL | |||
| 1BRS_A_D | ED76A | ED74A | RIM | 1BRS_A_D,1B2U_A_D... | 5.3E-10 | 1.32E-10 | Barnase | Barstar | 298 | 8.97E+05 | 8.74E+05 | 4.75E-04 | 1.15E-04 | None | None | None | None | SPR | |||
| 1EMV_A_B | IA53A | IA51A | SUP | 2VLP_A_B,2VLN_A_B... | 6.78E-14 | 1.62E-14 | Colicin E9 immunity protein | Colicin E9 DNase | 298 | 8.94E+07 | 1.13E+08 | 6.06E-06 | 1.83E-06 | None | None | None | None | SFFL | |||
| 1B41_A_B | HB29K | HB29K | RIM | 1B41_A_B,1FSS_A_B... | 2.1E-11 | 9.4E-11 | Human acetylcholinesterase | Fasciculin II | 298(assumed) | 8.92E+06 | 5.05E+06 | 1.87E-04 | 4.75E-04 | None | None | None | None | IASP |