SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
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PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
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<=
>=
starts with
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7085 records found
PDB Code
Mutation Pdb▼
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
4CPA_A_I
YI37F
YI36F
COR
4CPA_A_I,2ABZ_B_E
1.5E-09
1.5E-09
Carboxypeptidase A
Potato carboxypeptidase inhibitor
298(assumed)
None
None
None
None
IASP
2FTL_E_I
YI35A
YI35A
INT
Pr/PI
Pr/PI
<5E-11
5E-14
Bovine trypsin
BPTI
295
5.1E+05
9.9E+05
<2.6E-05
5E-08
None
None
None
None
IASP
1CBW_FGH_I
YI35A
YI35A
INT
Pr/PI
Pr/PI
5.49E-08
1.42E-08
Bovine alpha-chymotrypsin
BPTI
295
1.80
2.50
39.60
44.70
ITC
1CBW_FGH_I
YI35A
YI35A
INT
Pr/PI
Pr/PI
4.9E-08
1.1E-08
Bovine alpha-chymotrypsin
BPTI
295
1.8E+05
1.7E+05
8.9E-03
1.8E-03
None
None
None
None
IASP
1CHO_EFG_I
YI20W
YI17W
COR
Pr/PI
Pr/PI
1.02E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20W
YI20W
COR
Pr/PI
Pr/PI
2.44E-10
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
YI20W
YI15W
COR
Pr/PI
Pr/PI
1.59E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
YI20W
YI14W
COR
Pr/PI
Pr/PI
3.45E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
YI20V
YI17V
COR
Pr/PI
Pr/PI
1.82E-09
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
YI20V
YI20V
COR
Pr/PI
Pr/PI
1.92E-07
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
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