SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
Log In
Lost password?
Forgot username?
Log In
Download
Summary
Browse
News
FAQ/Help
Contact
Browse the database
Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2▼
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1GCQ_AB_C
GC611V
GC21V
COR
1GCQ_AB_C,1EFN_A_B
1.61E-05
1.68E-05
Growth factor receptor-bound protein 2
VavS
298
None
None
None
None
SPR
4U6H_AB_E
NE27A
NE21A
COR
AB/AG
AB/AG
5E-11
9E-11
M12B9 fab
Vaccinia L1
298(assumed)
5.59E+05
5.125E+05
6.4E-05
4.8E-05
None
None
None
None
BI
4U6H_AB_E
QE31A
QE25A
RIM
AB/AG
AB/AG
1.1E-10
9E-11
M12B9 fab
Vaccinia L1
298(assumed)
4.9E+05
5.125E+05
1.1E-04
4.8E-05
None
None
None
None
BI
4U6H_AB_E
DE35A
DE29A
COR
AB/AG
AB/AG
n.b
9E-11
M12B9 fab
Vaccinia L1
298(assumed)
None
None
None
None
BI
3BT1_A_U
RU137A
RU135A
INT
3BT1_A_U
5.6E-10
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
KU139A
KU137A
RIM
3BT1_A_U
2.84E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
RU142A
RU140A
SUR
3BT1_A_U
1.68E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
HU143A
HU141A
INT
3BT1_A_U
2.78E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
RU145A
RU143A
INT
3BT1_A_U
1.85E-09
9.1E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
298
None
None
None
None
SPR
3BT1_A_U
LU1A
LU1A
SUR
3BT1_A_U
8.2E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.65E+05
3.98E+05
2.18E-04
1.77E-04
None
None
None
None
SPR
<<
<
6
7
8
9
10
11
12
13
14
15
>
>>