SKEMPI v2.0

Download the database

Database summary

Browse the database

Submit new data

Latest News

Fixed 3SEK and 1JCK_A_B

We have fixed two errors in our database on 3SEK and 1JCK_A_B references.

Added missing 3QIB

3QIB added to cleaned PDB structures.

SKEMPI v2.0

SKEMPI version 2.0 has been released

Statistics

Total number of mutations: 7085

Reference

Jankauskaitė J, Jiménez-García B, Dapkūnas J, Fernández-Recio J, Moal IH (2019) SKEMPI 2.0: an updated benchmark of changes in protein–protein binding energy, kinetics and thermodynamics upon mutation. Bioinformatics 35, 462–469 (https://doi.org/10.1093/bioinformatics/bty635)