SKEMPI v2.0

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Mutations

7085 records found

PDB Code	Mutation Pdb	Mutation Cleaned	Location	Hold Out Type	Hold Out Proteins	Affinity Mut	Affinity Wt	Ref.	Protein 1	Protein 2	T (ºK)	Kon Mut	Kon Wt	Koff Mut	Koff Wt	Dh Mut	Dh Wt	Ds Mut	Ds Wt	Method
1A4Y_A_B	KB40G,YA434A,YA437A	KB40G,YA434A,YA437A	SUP,COR,COR		1A4Y_A_B,1Z7X_W_X	1.9E-09	3.9E-16		Ribonuclease inhibitor	Angiogenin	298	1E+07	2.8E+08	1.9E-02	1.1E-07	None	None	None	None	SFFL
1Z7X_W_X	YW434F	YW434F	COR		1Z7X_W_X,1A4Y_A_B	3.8E-14	3.1E-14		Ribonuclease inhibitor	RNase A	298	2.6E+08	3.8E+08	1E-05	1.2E-05	None	None	None	None	SFFL
1Z7X_W_X	YW437F	YW437F	COR		1Z7X_W_X,1A4Y_A_B	1.2E-12	3.1E-14		Ribonuclease inhibitor	RNase A	298	2.5E+08	3.8E+08	2.9E-04	1.2E-05	None	None	None	None	SFFL
1Z7X_W_X	YW434A,DW435A	YW434A,DW435A	COR,COR		1Z7X_W_X,1A4Y_A_B	5.6E-09	3.1E-14		Ribonuclease inhibitor	RNase A	298					None	None	None	None	SFFL
1Z7X_W_X	YW434A,YW437A	YW434A,YW437A	COR,COR		1Z7X_W_X,1A4Y_A_B	6.3E-09	3.1E-14		Ribonuclease inhibitor	RNase A	298					None	None	None	None	SFFL
1A22_A_B	MA14A	MA14A	INT		1A22_A_B,1BP3_A_B	9E-10	9E-10		Human growth hormone	hGH binding protein	298	3E+05	3E+05	3.24E-04	2.7E-04	None	None	None	None	SPR
1A22_A_B	HA18A	HA18A	COR		1A22_A_B,1BP3_A_B	3.96E-10	9E-10		Human growth hormone	hGH binding protein	298	2.73E+05	3E+05	1.11E-04	2.7E-04	None	None	None	None	SPR
1A22_A_B	HA21A	HA21A	SUP		1A22_A_B,1BP3_A_B	1.17E-09	9E-10		Human growth hormone	hGH binding protein	298	3E+05	3E+05	3.51E-04	2.7E-04	None	None	None	None	SPR
1A22_A_B	QA22A	QA22A	RIM		1A22_A_B,1BP3_A_B	6.21E-10	9E-10		Human growth hormone	hGH binding protein	298	2.73E+05	3E+05	1.67E-04	2.7E-04	None	None	None	None	SPR
1A22_A_B	FA25A	FA25A	COR		1A22_A_B,1BP3_A_B	4.23E-10	9E-10		Human growth hormone	hGH binding protein	298	3E+05	3E+05	1.27E-04	2.7E-04	None	None	None	None	SPR