SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
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<=
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starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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!=
<
>
<=
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in
not in
=
!=
<
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<=
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starts with
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
contains
in
not in
=
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
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<
>
<=
>=
=
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<
>
<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1PPF_E_I
LI18E
LI18E
COR
Pr/PI
Pr/PI
2.44E-05
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
LI18H
LI18H
COR
Pr/PI
Pr/PI
9.09E-06
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
LI18F
LI18F
COR
Pr/PI
Pr/PI
1.01E-06
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
LI18R
LI18R
COR
Pr/PI
Pr/PI
3.03E-05
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
LI18Y
LI18Y
COR
Pr/PI
Pr/PI
1.2E-05
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
LI18W
LI18W
COR
Pr/PI
Pr/PI
5.56E-05
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
LI18G
LI13G
COR
Pr/PI
Pr/PI
1.56E-09
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
LI18A
LI13A
COR
Pr/PI
Pr/PI
5E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
LI18S
LI13S
COR
Pr/PI
Pr/PI
4.17E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
LI18C
LI13C
COR
Pr/PI
Pr/PI
3.03E-12
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
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