SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1R0R_E_I
AI15W
AI10W
COR
Pr/PI
Pr/PI
4.17E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15G
AI9G
COR
Pr/PI
Pr/PI
1.19E-09
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15S
AI9S
COR
Pr/PI
Pr/PI
8.33E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15C
AI9C
COR
Pr/PI
Pr/PI
1.92E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15V
AI9V
COR
Pr/PI
Pr/PI
4.76E-12
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15T
AI9T
COR
Pr/PI
Pr/PI
3.13E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15P
AI9P
COR
Pr/PI
Pr/PI
4.55E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15L
AI9L
COR
Pr/PI
Pr/PI
2.38E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15I
AI9I
COR
Pr/PI
Pr/PI
8.33E-12
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
AI15M
AI9M
COR
Pr/PI
Pr/PI
2.08E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
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