SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
Log In
Lost password?
Forgot username?
Log In
Download
Summary
Browse
News
FAQ/Help
Contact
Browse the database
Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1R0R_E_I
RI21E
RI16E
RIM
Pr/PI
Pr/PI
5.26E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
RI21H
RI16H
RIM
Pr/PI
Pr/PI
7.14E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
RI21F
RI16F
RIM
Pr/PI
Pr/PI
6.25E-11
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
RI21Y
RI16Y
RIM
Pr/PI
Pr/PI
1.18E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
RI21W
RI16W
RIM
Pr/PI
Pr/PI
1.45E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
RI21G
RI15G
RIM
Pr/PI
Pr/PI
1.16E-10
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
RI21A
RI15A
RIM
Pr/PI
Pr/PI
1.96E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
RI21S
RI15S
RIM
Pr/PI
Pr/PI
2.86E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
RI21C
RI15C
RIM
Pr/PI
Pr/PI
4.55E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
RI21V
RI15V
RIM
Pr/PI
Pr/PI
1.72E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
<<
<
266
267
268
269
270
271
272
273
274
275
>
>>
