SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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<
>
<=
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starts with
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in
not in
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!=
<
>
<=
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in
not in
=
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<
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<=
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starts with
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not in
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<
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<=
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starts with
contains
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not in
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<
>
<=
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starts with
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in
not in
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<
>
<=
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starts with
contains
in
not in
=
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
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<
>
<=
>=
=
!=
<
>
<=
>=
=
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<
>
<=
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=
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<
>
<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3SGB_E_I
NI36K
NI30K
RIM
Pr/PI
Pr/PI
4.76E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36Q
NI30Q
RIM
Pr/PI
Pr/PI
2.7E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36E
NI30E
RIM
Pr/PI
Pr/PI
9.09E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36H
NI30H
RIM
Pr/PI
Pr/PI
1.45E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36F
NI30F
RIM
Pr/PI
Pr/PI
1.41E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36R
NI30R
RIM
Pr/PI
Pr/PI
4.76E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36Y
NI30Y
RIM
Pr/PI
Pr/PI
1.49E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
NI36W
NI30W
RIM
Pr/PI
Pr/PI
4.35E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
TI17K,LI18R
TI14K,LI15R
COR,COR
Pr/PI
Pr/PI
1.45E-06
4.83E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
IASP
1CHO_EFG_I
TI17R,LI18R
TI14R,LI15R
COR,COR
Pr/PI
Pr/PI
9.58E-07
4.83E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
IASP
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