SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3BTQ_E_I
QI515K
QI13K
COR
Pr/PI
Pr/PI
5.88E-14
4.35E-07
Bovine trypsin
BPTI
295
None
None
None
None
IASP
3BTW_E_I
WI515K
WI13K
COR
Pr/PI
Pr/PI
5.88E-14
1.32E-07
Bovine trypsin
BPTI
295
None
None
None
None
IASP
3BTT_E_I
TI515K
TI13K
COR
Pr/PI
Pr/PI
5.88E-14
3.45E-06
Bovine trypsin
BPTI
295
None
None
None
None
IASP
2SGP_E_I
PI18L
PI13L
COR
Pr/PI
Pr/PI
1.79E-11
2.78E-05
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
1CSO_E_I
II18L
II13L
COR
Pr/PI
Pr/PI
1.79E-11
3.45E-08
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
1CT0_E_I
SI18L
SI13L
COR
Pr/PI
Pr/PI
1.79E-11
2E-08
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
1CT2_E_I
TI18L
TI13L
COR
Pr/PI
Pr/PI
1.79E-11
4E-09
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
1CT4_E_I
VI18L
VI13L
COR
Pr/PI
Pr/PI
1.79E-11
3E-09
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
2SGQ_E_I
QI18L
QI13L
COR
Pr/PI
Pr/PI
1.79E-11
1.45E-09
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
1SGD_E_I
DI18L
DI13L
COR
Pr/PI
Pr/PI
1.79E-11
2.56E-07
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
SP
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