SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
Log In
Lost password?
Forgot username?
Log In
Download
Summary
Browse
News
FAQ/Help
Contact
Browse the database
Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3BT1_A_U
EU178A
EU176A
SUR
3BT1_A_U
4.8E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.84E+05
3.98E+05
1.38E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
GU179A
GU177A
SUR
3BT1_A_U
8E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
3.7E+05
3.98E+05
2.95E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
PU180A
PU178A
SUR
3BT1_A_U
2.9E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
5.57E+05
3.98E+05
1.64E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
IU181A
IU179A
INT
3BT1_A_U
8.5E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.44E+05
3.98E+05
2.07E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
LU182A
LU180A
SUR
3BT1_A_U
1.43E-09
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.46E+05
3.98E+05
3.52E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
EU183A
EU181A
SUR
3BT1_A_U
1E-09
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.69E+05
3.98E+05
2.59E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
LU184A
LU182A
INT
3BT1_A_U
1.58E-09
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.19E+05
3.98E+05
3.47E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
EU185A
EU183A
SUR
3BT1_A_U
8.9E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.31E+05
3.98E+05
2.05E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
NU186A
NU184A
SUR
3BT1_A_U
8E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
2.74E+05
3.98E+05
2.19E-04
1.77E-04
None
None
None
None
SPR
3BT1_A_U
LU187A
LU185A
INT
3BT1_A_U
6.5E-10
4.6E-10
Urokinase-type plasminogen activator
Urokinase plasminogen activator surface receptor
293
3.79E+05
3.98E+05
2.46E-04
1.77E-04
None
None
None
None
SPR
<<
<
443
444
445
446
447
448
449
450
451
452
>
>>