SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1JTG_A_B
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- Mutation(s) in PDB:
EA239K
- Mutation(s) cleaned: EA213K
- Location: COR
- Hold out type:
- Hold out protein(s): 1XXM_A_C,1S0W_A_C,1JTG_A_B,2G2U_A_B,2G2W_A_B,3N4I_A_B,1JTD_A_B,3QHY_A_B
- Affinity mutant: 1.4E-10
- Affinity wild-typen: 2.8E-10
- Reference: 27956635
- Protein 1: TEM-1 beta-lactamase
- Protein 2: BLIP
- Method: SPR,SFFL
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1.5E+06
- Kon wild-type (M-1s-1): 3E+05
- Koff mutatant (M-1s-1): 1.6E-04
- Koff wild-type (M-1s-1): 8.5E-05
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None