SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1HE8_A_B
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- Mutation(s) in PDB:
KA223V,
KA234A
- Mutation(s) cleaned: KA80V,KA91A
- Location: SUP,RIM
- Hold out type:
- Hold out protein(s): 1HE8_A_B,4G0N_A_B,3KUD_A_B,1LFD_A_B,1K8R_A_B,5UFE_A_B,5UFQ_A_C,5TAR_A_B,1GUA_A_B,1C1Y_A_B
- Affinity mutant: 1.7E-05
- Affinity wild-typen: 1.3E-06
- Reference: 11136978
- Protein 1: Phosphatidylinositol 3-kinase
- Protein 2: H-Ras1
- Method: SFFL
- Temperaute: 293 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None