SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1CBW_FGH_I
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- Mutation(s) in PDB:
GI12A
- Mutation(s) cleaned: GI12A
- Location: SUP
- Hold out type: Pr/PI
- Hold out protein(s): Pr/PI
- Affinity mutant: 3.92E-08
- Affinity wild-typen: 1.42E-08
- Reference: 8784199
- Protein 1: Bovine alpha-chymotrypsin
- Protein 2: BPTI
- Method: ITC
- Temperaute: 295 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -0.6
- ΔH wild-type (kcal mol-1)): 2.5
- ΔS mutant (cal mol-1 K-1): 32.2
- ΔS wild-type (cal mol-1 K-1): 44.7